eBook - ePub
Amyloid Fibrils and Prefibrillar Aggregates
Molecular and Biological Properties
- English
- ePUB (mobile friendly)
- Available on iOS & Android
eBook - ePub
About this book
Summing up almost a decade of biomedical research, this topical and eagerly awaited handbook is the first reference on the topic to incorporate recent breakthroughs in amyloid research.
The first part covers the structural biology of amyloid fibrils and pre-fibrillar assemblies, including a description of current models for amyloid formation. The second part looks at the diagnosis and biomedical study of amyloid in humans and in animal models, while the final section discusses pharmacological approaches to manipulating amyloid and also looks at its physiological roles in lower and higher organisms. For Biochemists, Molecular Biologists, Neurobiologists, Neurophysiologists and those working in the Pharmaceutical Industry.
The first part covers the structural biology of amyloid fibrils and pre-fibrillar assemblies, including a description of current models for amyloid formation. The second part looks at the diagnosis and biomedical study of amyloid in humans and in animal models, while the final section discusses pharmacological approaches to manipulating amyloid and also looks at its physiological roles in lower and higher organisms. For Biochemists, Molecular Biologists, Neurobiologists, Neurophysiologists and those working in the Pharmaceutical Industry.
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Please note we cannot support devices running on iOS 13 and Android 7 or earlier. Learn more about using the app.
Yes, you can access Amyloid Fibrils and Prefibrillar Aggregates by Daniel Erik Otzen in PDF and/or ePUB format, as well as other popular books in Biowissenschaften & Molekularbiologie. We have over one million books available in our catalogue for you to explore.
Information
Table of contents
- Cover
- Related Titles
- Title Page
- Copyright
- Preface
- List of Contributors
- Chapter 1: The Amyloid Phenomenon and Its Significance
- Chapter 2: Amyloid Structures at the Atomic Level: Insights from Crystallography
- Chapter 3: What Does Solid-State NMR Tell Us about Amyloid Structures?
- Chapter 4: From Molecular to Supramolecular Amyloid Structures: Contributions from Fiber Diffraction and Electron Microscopy
- Chapter 5: Structures of Aggregating Species by Small-Angle X-Ray Scattering
- Chapter 6: Structural and Compositional Information about Pre-Amyloid Oligomers
- Chapter 7: The Oligomer Species: Mechanistics and Biochemistry
- Chapter 8: Pathways of Amyloid Formation
- Chapter 9: Sequence-Based Prediction of Protein Behavior
- Chapter 10: The Kinetics and Mechanisms of Amyloid Formation
- Chapter 11: Fluorescence Spectroscopy as a Tool to Characterize Amyloid Oligomers and Fibrils
- Chapter 12: Animal Models of Amyloid Diseases
- Chapter 13: The Role of Aβ in Alzheimer's Disease
- Chapter 14: Experimental Approaches to Inducing Amyloid Aggregates
- Chapter 15: Fibrillar Polymorphism
- Chapter 16: Inhibitors of Amyloid and Oligomer Formation
- Chapter 17: Development of Therapeutic Strategies for the Transthyretin Amyloidoses
- Chapter 18: Hormone Amyloids in Sickness and in Health
- Chapter 19: Functional Amyloids in Bacteria
- Chapter 20: Structural Properties and Applications of Self-Assembling Peptides
- Chapter 21: Harnessing the Self-Assembling Properties of Proteins in Spider Silk and Lung Surfactant
- Index