Frozen Section In Surgical Pathology

An Atlas Volume 2

Joseph Kovi

• Publisher: CRC Press
• Year: 2019
• eBook ISBN: 9780429558610
• Edition: 1
• Topic: Medicine
• Subtopic: Medical Theory, Practice & Reference

Published in 1983: In this Atlas the discussion of equipment, technique, its nuances, and problems is followed by clinical and pathological presentations.

TABLE OF CONTENTS

Volume I

Chapter 1
Introduction

I. Frozen Section Diagnosis

A. Indications for Frozen Section Examination

B. Reliability of the Frozen Section Diagnosis

C. Limitations of the Frozen Section Method

II. Sources of Error

A. The Role of the Surgeon

B. Shortcomings of the Pathologist

Chapter 2
Cryostat Frozen Sections

I. The Instrument

II. The Microtome Knife

III. Section Thickness

IV. Specimen Installation and Alignment

V. Anti-Roll System

VI. Specimen Mounting

VII. Sectioning Technique

VIII. General Sectioning Procedure

IX. Section Mounting

A. Warm Slide

B. Cold Slide

X. Section Fixation

XI. A Rapid Η & Ε Staining Procedure

Chapter 3
Breast

I. Introduction

II. Normal Lobule

III. Cystic Lobular Involution

IV. Chronic Abscess

V. Plasma Cell Mastitis

VI. Mammary Duct Ectasia

VII. Fat Necrosis

VIII. Fibrocystic Disease

IX. Fibrous Disease of the Breast

X. Sclerosing Adenosis (Adenosis Tumor)

XI. Adenoma of the Nipple

XII. Fibroadenoma

XIII. Lactating Adenoma

XIV. Solitary Intraductal Papilloma

XV. Granular Cell Tumor

XVI. Cystosarcoma Phylloides, Histologically Benign

XVII. Gynecomastia

XVIII. Intraductal Carcinoma

XIX. Invasive Duct Carcinoma

XX. Medullary Carcinoma

XXI. Mucinous Carcinoma

XXII. Well Differentiated (Tubular) Carcinoma

XXIII. Adenoid Cystic Carcinoma

XXIV. Paget’s Disease

XXV. Infiltrating Papillary Carcinoma

XXVI. Lobular Carcinoma

Chapter 4
Lymph Node

I. Introduction

A. The Surgeon’s Role in Lymph Node Biopsies

B. Lymph Node: Normal Structure

Part A: Reactive Processes

I. Reactive Follicular Hyperplasia

II. Sinus Histiocytosis

III. Chronic Lymphadenitis

Part B: Granulomatous Inflammation

I. Lipogranulomatous Reaction (Lipophagic Granuloma)

II. Noncaseating Granuloma (Sarcoidosis)

III. Caseating Granuloma (Tuberculosis)

Part C: Metastatic Carcinoma

I. Introduction

II. Metastatic Adenocarcinoma

III. Metastatic Mucinous Carcinoma

IV. Metastatic Squamous Cell Carcinoma

V. Metastatic Anaplastic Carcinoma

VI. Hodgkin’s Disease

Part D: Non-Hodgkin’s Lymphoma

I. Nodular (Follicular) Lymphoma

II. Well Differentiated Lymphocytic Lymphoma, Diffuse

III. Malignant Lymphoma, Diffuse, Mixed, Small and Large Cell

Chapter 5
Lung

I. Introduction

II. Indications for Frozen Section Examination in Pulmonary Surgery

III. Solitary Pulmonary Nodule (SPN)

IV. Handling of Lung Specimens

V. Organizing Pneumonia

VI. Sarcoidosis

VII. Hamartoma

VIII. Bronchogenic Carcinoma

A. Sex Related Incidence of Lung Cancer

B. The Role of Electron Microscopy in the Diagnosis of Bronchogenic Carcinoma

IX. Squamous Cell Carcinoma

X. Small Cell Undifferentiated Carcinoma

XI. Adenocarcinoma

XII. Bronchioloalveolar Carcinoma

XIII. Large Cell Undifferentiated Carcinoma

XIV. Carcinoid Tumor

Chapter 6
Thyroid Gland

I. Introduction

II. Exploration of the Thyroid Gland

III. Riedel’s Struma (Invasive Thyroiditis)

IV. Subacute (Granulomatous or de Quervain’s) Thyroiditis

V. Lymphocytic Thyroiditis

VI. Adenomatous Goiter (Nodular Hyperplasia)

VII. Follicular Adenoma

VIII. Papillary Carcinoma

IX. Follicular Carcinoma

Chapter 7
Brain

I. Introduction

A. The Surgeon’s Role in Brain (CNS) Biopsies

B. Ancillary Frozen Section Techniques

II. Astrocytoma

III. Glioblastoma Multiforme

IV. Mixed Oligodendroglioma-Astrocytoma

V. Medulloblastoma

VI. Meningioma

VII. Germinoma

VIII. Metastatic Carcinoma

References

Index

Volume II

Chapter 1
Gastrointestinal Tract

Part A: Esophagus

I. Squamous Cell Carcinoma

Part B: Stomach

I. Signet Ring Cell Carcinoma

II. Leiomyoma

III. Leiomyosarcoma

Part C: Large Bowel

I. Adenomatous Polyp

II. Mixed Villous and Adenomatous Polyp

III. Mucinous Adenocarcinoma (Cecum)

IV. Adenocarcinoma, NOS (Sigmoid Colon)

V. Adenocarcinoma (Rectum)

VI. Hirschsprung’s Disease (Congenital Megacolon)

Chapter 2
Soft Tissues

I. Introduction

A. Surgical Management of Soft Tissue Sarcomas

B. Clinical Information

C. Handling of Soft Tissue Specimens

D. Common Problems Encountered in Frozen Sections of Soft Tissue Lesions

E. The Frozen Section Report

II. Tumoral Calcinosis

III. Keloid

IV. Nodular Fascitis

V. Musculoaponeurotic Fibromatosis

VI. Fibrosarcoma

VII. Dermatofibroma

VIII. Dermatofibrosarcoma Protuberans

IX. Malignant Fibrous Histiocytoma (MFH)

X. Neurilemoma

XI. Neurofibroma

XII. Lipoma

XIII. Liposarcoma

XIV. Lymphangioma

XV. Malignant Hemangiopericytoma

XVI. Angiosarcoma

XVII. Leiomyoma

XVIII. Leiomyosarcoma

XIX. Pleomorphic Rhabdomyosarcoma

XX. Embryonal Rhabdomyosarcoma

XXI. Alveolar Rhabdomyosarcoma

XXII. Granular Cell Tumor

XXIII. Alveolar Soft Part Sarcoma

Chapter 3
Bone

I. Introduction

II. Ewing’s Sarcoma

III. Reticulum Cell Sarcoma

IV. Giant Cell Tumor

V. Metastatic Cancer

VI. Ameloblastoma

Chapter 4
Female Reproductive System

Part A: Cervix

I. Invasive Squamous Cell Carcinoma

Part B: Endometrium

A. Proliferative Phase

B. Secretory Endometrium

C. Pregnancy Related Changes in Endometrial Curettings

D. Endometrial Hyperplasia

E. Endometrial Polyp

F. Adenocarcinoma of the Endometrium

G. Endometrial Stromal Sarcoma

H. Comment

Part C: Ovarian Tumors

Chapter 5
Parathyroid

Primary Hyperparathyroidism

Chapter 6
Miscellaneous

I. Pancreas

A. Normal Pancreas

B. Chronic Fibrosing Pancreatitis

C. Pseudocyst

D. Microcystic Adenoma

E. Adenocarcinoma

F. Islet Cell Tumor

II. Squamous Cell Carcinoma of Head and Neck

III. Tumors of the Major Salivary Glands

A. Pleomorphic Adenoma (Mixed Tumor)

B. Warthin’s Tumor (Papillary Cystadenoma Lymphomatosum, Adenolymphoma)

C. Mucoepidermoid Carcinoma

D. Undifferentiated Carcinoma

IV. Male Reproductive System

A. Carcinoma of the Prostate

B. Testis

V. Skin Tumors

A. Basal Cell Epithelioma (BCE)

B. Squamous Cell Carcinoma

C. Malignant Melanoma

D. Comment

E. Intradermal Nevus

F. Metastatic Neoplasms

VI. Liver

A. Normal Liver

B. Early Passive Congestion

C. Cholestasis

D. Cirrhosis

E. Nodular Regenerative Hyperplasia

F. Liver Cell Carcinoma (Hepatoma)

G. Metastatic Neoplasms

H. Comment

VII. Kidney and Ureter

A. Renal Cell Carcinoma

B. Renal Allograft Rejection

VIII. Pituitary Adenoma

IX. Thymus

A. Thymoma

X. Carotid Body Paraganglioma

References

Index

Chapter 1

GASTROINTESTINAL TRACT

Part A: Esophagus

I. Squamous Cell Carcinoma

A 60-year-old black man was admitted to the hospital complaining of difficulty in ingesting solid foods and even liquids. The patient lost more than 30 lbs in the last 6 months. He admitted to having been a heavy smoker and drinker in his life. X-Ray examination of the esophagus revealed an irregular, ragge...

Table of contents

• Cover
• Title Page
• Copyright Page
• Foreword
• Introduction
• The Author
• Acknowledgment
• Dedication
• Table of Contents
• References
• Index