Animal Models in Toxicology
eBook - PDF

Animal Models in Toxicology

Shayne C. Gad, Shayne C. Gad, Shayne C. Gad

Share book
  1. 1,152 pages
  2. English
  3. PDF
  4. Available on iOS & Android
eBook - PDF

Animal Models in Toxicology

Shayne C. Gad, Shayne C. Gad, Shayne C. Gad

Book details
Book preview
Table of contents
Citations

About This Book

Animal Models in Toxicology is a single-source reference for the use of animal models in toxicology. Chapters cover nine species used in toxicology and experimental biology. With contributions from experts in toxicology, toxicological pathology, and species-specific metabolism, each of these chapters provides an excellent introductory "course" alon

Frequently asked questions

How do I cancel my subscription?
Simply head over to the account section in settings and click on “Cancel Subscription” - it’s as simple as that. After you cancel, your membership will stay active for the remainder of the time you’ve paid for. Learn more here.
Can/how do I download books?
At the moment all of our mobile-responsive ePub books are available to download via the app. Most of our PDFs are also available to download and we're working on making the final remaining ones downloadable now. Learn more here.
What is the difference between the pricing plans?
Both plans give you full access to the library and all of Perlego’s features. The only differences are the price and subscription period: With the annual plan you’ll save around 30% compared to 12 months on the monthly plan.
What is Perlego?
We are an online textbook subscription service, where you can get access to an entire online library for less than the price of a single book per month. With over 1 million books across 1000+ topics, we’ve got you covered! Learn more here.
Do you support text-to-speech?
Look out for the read-aloud symbol on your next book to see if you can listen to it. The read-aloud tool reads text aloud for you, highlighting the text as it is being read. You can pause it, speed it up and slow it down. Learn more here.
Is Animal Models in Toxicology an online PDF/ePUB?
Yes, you can access Animal Models in Toxicology by Shayne C. Gad, Shayne C. Gad, Shayne C. Gad in PDF and/or ePUB format, as well as other popular books in Medicine & Pharmacology. We have over one million books available in our catalogue for you to explore.

Information

Publisher
CRC Press
Year
2016
ISBN
9781466554290
Edition
3
Topic
Medicine
Subtopic
Pharmacology
1
CHAPTER 
1
Introduction
Shayne 
Cox 
Gad
BACKGROUND
The.
use.
of.
animals.
in.
experimental.
medicine,.
pharmacology,.
pharmaceutical.
and.
medical.
device.development,.safety.assessment,.and.toxicological.evaluation.is.a.well-established,.regulato-
rily.required,.and.essential.practice
.
.Whether.serving.as.a.source.of.isolated.organelles,.cells,.or.tis-
sues,.a.disease.model,.or.a.predictive.model.for.drug.or.other.xenobiotic.action.or.transformation.in.
man,.animal.models.have.provided.the.necessary.building.blocks.that.have.permitted.the.explosive.
growth.of.medical.and.biological.knowledge.in.the.later.half.of.the.twentieth.century.and.into.the.
CONTENTS
Background.
........................................................................................................................................
1
Current.Animal.Studies.
.....................................................................................................................
2
Origins.of.Predictive.Animal.Testing.
................................................................................................
3
“Lash.Lure”.Case.
..........................................................................................................................
3
Elixir.of.Sulfanilamide.Case.
........................................................................................................
3
Thalidomide.
..................................................................................................................................
3
Selecting.an.Animal.Model.
...............................................................................................................
5
Husbandry.and.Care.
..........................................................................................................................
6
Caging.
...........................................................................................................................................
6
Choosing.Species.and.Strains.
............................................................................................................
7
Dosing.
................................................................................................................................................
7
Animal.Physiology.
.............................................................................................................................
8
Background.Incidence.of.Disease.and.Neoplasia.
.........................................................................
8
Responses.to.Biologically.Active.Agents.
......................................................................................
8
Absorption,.Distribution,.Metabolism,.and.Excretion.of.Xenobiotics.
.........................................
9
Absorption.
..............................................................................................................................
10
Distribution.
.............................................................................................................................
10
Metabolism.
.............................................................................................................................
11
Excretion.
................................................................................................................................
12
Summary.
..........................................................................................................................................
16
References.
........................................................................................................................................
16

Table of contents