Cutaneous Melanoma

A Pocket Guide for Diagnosis and Management

Giuseppe Argenziano, Aimilios Lallas, Caterina Longo, Elvira Moscarella, Athanassios Kyrgidis, Gerardo Ferrara

• Publisher: Academic Press
• Year: 2017
• Print ISBN: 9780128040003
• eBook ISBN: 9780128040317
• Topic: Medicine
• Subtopic: Oncology

Cutaneous Melanoma: A Pocket Guide for Diagnosis and Management serves as an easy-to-consult, short, and schematic reference providing guidelines for diagnosing and managing melanoma in the context of various clinical scenarios. In the daily routine of a busy clinician, there is a need for schematic reference tools that allow quick consultation for immediate decisions. Melanoma is a deadly disease that should be promptly managed following precise and evidence-based guidelines.The guide contains many schematics and figures, vastly outnumbering the pages dedicated to text. This guide follows the sequence of a real clinical setting, going from the first screening visit to the final stages of terminal patients.- Provides a quick-access resource for diagnosis and treatment of melanoma patients at all stages- Includes succinct guidelines, schematics, and figures for busy clinicians- Concludes with a section addressing special clinical situations, including melanoma in pregnancy, pediatric melanoma, familial melanoma and MPM, atypical Spitz tumor, occult primary melanoma, and the histopathologic gray zone

Chapter 1

Melanoma Epidemiology

Athanassios Kyrgidis Aristotle University of Thessaloniki, Thessaloniki, Greece

Abstract

The incidence of melanoma is rising faster than that of any other type of cancer while mortality rates are not rising or remain stable in many countries. Melanoma is rare in nonwhites, but when present its associated mortality rate is higher. Melanoma is extremely rare prior to puberty. The distribution of skin melanoma in the different body areas is not homogeneous.

Keywords

melanoma

mortality

incidence

survival

ethnicity

race

Outline

1 Incidence and Mortality

2 Survival

3 Europe

4 Race/Ethnicity

5 Age

6 Body Location

References

1. Incidence and Mortality

The incidence of melanoma is rising faster than that of any other type of cancer while mortality rates are not rising or remain stable in many countries [1–7]:

• US incidence of melanoma: 60,000 new cases per year (about 4% of all newly diagnosed cancers).

• US average mortality: 8000 people per year.

• Approximately 1 out of 50–60 Americans alive today will develop melanoma in their lifetime (Lifetime Risk of Developing Cancer: 2.1%, approximately).

• Based on 2008–12 cases in the United States, the age-adjusted number of new cases of melanoma of the skin is 21.6 per 100,000 men and women per year. The age-adjusted number of deaths is 2.7 per 100,000 men and women per year [1,8].

In the United States, incidence rates for new melanoma of the skin have been rising on average 1.4% each year over the past 10 years. Death rates have been stable over 2002–12. There are two possible explanations:

• Patients present at an earlier stage of tumor development.

• There has been a significant increase in screening for melanoma with a large number of very borderline and very thin melanomas diagnosed.

Fig. 1.1, which presents mortality and death trends in the United States in the past 30 years, clearly demonstrates this fact.

Figure 1.1 Trends in melanoma: new cases and deaths per 100,000 persons in the United States in the ...

Table of contents

• Cover
• Title page
• Table of Contents
• Copyright
• Contributors
• Cutaneous Melanoma: A Pocket Guide for Diagnosis and Management
• Chapter 1: Melanoma Epidemiology
• Chapter 2: Risk Factors
• Chapter 3: Diagnosis of Primary Melanoma
• Chapter 4: Melanoma Staging
• Chapter 5: Therapy of Melanoma
• Chapter 6: Follow-Up of Disease-Free Patients
• Chapter 7: Special Clinical Situations
• Index