The Somatotrophic Axis in Brain Function
eBook - ePub

The Somatotrophic Axis in Brain Function

  1. 384 pages
  2. English
  3. ePUB (mobile friendly)
  4. Available on iOS & Android
eBook - ePub

The Somatotrophic Axis in Brain Function

About this book

The somatotropic axis is one of the major hormonal systems regulating postnatal growth in mammals. It interacts with the central nervous system on several levels. Growth hormone (GH) and insulin-like growth factor-I (IGF-I) receptors are expressed in many brain areas including the hippocampus, pituitary and hypothalamus. GH and IGF-I are important factors in the development and differentiation of the CNS and have protective properties in dementia, as well as in traumatic and ischaemic injury of the CNS. Also GH has an important impact on mood and well-being with GH secretory capacity being reduced in depression.This volume will include chapters (1) on basic knowledge on GH/IGF-1, (2) on localization of GH/IGF-1 and their receptors in the CNS, including blood brain barrier transport of both hormones, (3) on actions of the two hormones on CNS function (basic science), (4) on clinical aspects of GH/IGF-1 in relation to various CNS functions and disorders, and finally (5) on some future perspectives in this area of science.Contents are well balanced and cover a variety of relevant topics from basic to clinical researchInternational selection of authors, with a good representation of the research on growth hormonesA timely publication which will be useful to scientists in both basic and clinical research

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Yes, you can access The Somatotrophic Axis in Brain Function by Fred Nyberg in PDF and/or ePUB format, as well as other popular books in Medicine & Neurology. We have over one million books available in our catalogue for you to explore.

Information

Publisher
Academic Press
Year
2005
eBook ISBN
9780080498164
Topic
Medicine
Subtopic
Neurology

Table of contents

  1. Cover image
  2. Title page
  3. Table of Contents
  4. Preface
  5. Contributors
  6. Pioneers in the growth hormone field
  7. Section 1: Biosynthesis of Growth Hormone and Insulin-like Growth Factor-I and Regulation of Their Secretion
  8. Section 2: Growth Hormone and Insulin-like Growth Factor-I and their Function at the Receptor Level
  9. Section 3: Growth Hormone and Insulin-like Growth Factors and Their Receptors in the Central Nervous System
  10. Section 4: Central Nervous System Action of Growth Hormone: Basic Studies Using Animal Models
  11. Section 5: Immediate and Long-Term Benefits on the Central Nervous System and Growth Hormone Replacement Therapy
  12. Section 6: Growth Hormone Replacement and Related Therapies in Central Nervous System Disorders: A Future Perspective
  13. Index