Quantitative Structure-Activity Relationships of Drugs
eBook - PDF

Quantitative Structure-Activity Relationships of Drugs

  1. 534 pages
  2. English
  3. PDF
  4. Available on iOS & Android
eBook - PDF

Quantitative Structure-Activity Relationships of Drugs

About this book

Medicinal Chemistry, Volume 19: Quantitative Structure-Activity Relationships of Drugs is a critical review of the applications of various quantitative structure-activity relationship (QSAR) methodologies in different drug therapeutic areas and discusses the results in terms of their contribution to medicinal chemistry. After briefly describing the developments in QSAR research, this 12-chapter volume goes on discussing the contributions of QSAR methodology in elucidating drug action and rational development of drugs against bacterial, fungal, viral, and other parasitic infections of man. Other chapters explore the mode of action and QSAR of antitumor, cardiovascular, antiallergic, antiulcer, antiarthritic, and nonsteroidal antiinflammatory drugs (NSAID) agents. The discussion then shifts to the pharmacologic effects and QSAR analysis of central nervous system agents, steroids, and other hormones. A chapter examines the major chemicals affecting insects and mites, with particular emphasis on the parameters of binding correlation and reactivity for insect and mite enzymes. The concluding chapters cover the limitations of the QSAR approach in the quantitative treatment of drug absorption, distribution, and metabolism. This volume is of great value to medicinal chemists, scientists, and researchers.

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Yes, you can access Quantitative Structure-Activity Relationships of Drugs by John Topliss in PDF and/or ePUB format, as well as other popular books in Medicine & Pharmacology. We have over one million books available in our catalogue for you to explore.

Information

Year
2012
Print ISBN
9780126951509
eBook ISBN
9780323146876
Subtopic
Pharmacology

Table of contents

  1. Front Cover
  2. Quantitative Structure–Activity Relationships of Drugs
  3. Copyright Page
  4. Table of Contents
  5. Contributors
  6. Preface
  7. Chapter 1. Introduction: A Review of QSAR Methodology
  8. Chapter 2. Synthetic Antiinfective Agents
  9. Chapter 3. Semisynthetic Antibiotics
  10. Chapter 4. Antitumor Agents
  11. Chapter 5. Cardiovascular Agents
  12. Chapter 6. Antiallergic and Antiulcer Agents
  13. Chapter 7. Nonsteroidal Antiinflammatory and Antiarthritic Drugs
  14. Chapter 8. Agents Affecting the Central Nervous System
  15. Chapter 9. Steroids and Other Hormones
  16. Chapter 10. Chemicals Affecting Insects and Mites
  17. Chapter 11. Absorption, Distribution, and Metabolism of Drugs
  18. Chapter 12. Commentary
  19. Index