Studies in Natural Products Chemistry
eBook - PDF

Studies in Natural Products Chemistry

Stereoselective Synthesis

  1. 938 pages
  2. English
  3. PDF
  4. Available on iOS & Android
eBook - PDF

Studies in Natural Products Chemistry

Stereoselective Synthesis

About this book

Studies in Natural Products Chemistry, Volume 14: Stereoselective Synthesis, Part I is a collection of discourses on the stereoselective synthesis of the anticancer anthrucycline antibiotics; tetramic acid antibiotics; 3-and 4-deoxyhexoses; polysaccharides; levoglucosenone as precursor to natural products; synthesis of oligoribonucleotides; and oxidation of guaiazulene. This volume deals with a broad range of natural products focusing on the synthesis of antibiotics and anticancer agents — anthracyclines, tetramic acid, taxodione, vinblastine, and vincristine. These aforementioned drugs are used for the treatment of cancer (anthracyclines) and Hodgkin's disease and childhood acute leukemia (vinblastine and vincristine). The importance of the latest developments in the stereocontrolled synthesis of polysaccharides is discussed as polysaccharides play a fundamental role in cell life and have many technical applications. The synthesis of bioactive carbohydrates 3- and 4-deoxy-hexoses is compared with the more occurring deoxyhexoses in nature such as the 2-deoxy, 6-deoxy, and 2, 6-dideoxy-hexoses, because the former are rare compounds and useful tools in the study of biological and biochemical properties of mono- and oligosaccharides, glycoproteins, and antibiotics. Alkaloids derived from Apocynaceae are known for their medicinal properties; hence the synthetic approaches to vinblastine and vincristine are discussed. Because of the minute amounts available from herbal sources, efforts toward their chemical synthesis are given more reference. This book can be a useful reference for the organic chemists. Chemical researchers, pharmaceutical scientists, and professionals of bioorganic chemistry will likewise gain a lot from this collection.

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Yes, you can access Studies in Natural Products Chemistry by Atta-ur-Rahman in PDF and/or ePUB format, as well as other popular books in Physical Sciences & Chemistry. We have over one million books available in our catalogue for you to explore.

Information

Publisher
Elsevier
Year
2013
Print ISBN
9780444817808
eBook ISBN
9781483163536
Topic
Physical Sciences
Subtopic
Chemistry
Index
Chemistry

Table of contents

  1. Front Cover
  2. Stereoselective Synthesis (Part I)
  3. Copyright Page
  4. Table of Contents
  5. FOREWORD
  6. PREFACE
  7. CONTRIBUTORS
  8. Stereoselective Synthesis
  9. CHAPTER 1. STEREOSELECTIVE SYNTHESES OF DOXORUBICIN AND RELATED COMPOUNDS
  10. CHAPTER 2. TOTAL SYNTHESIS OF NOGALAMYCIN CONGENERS AND THEIR RELATED COMPOUNDS
  11. CHAPTER 3. SYNTHESIS OF THE TETRANIIC ACID ANTIBIOTICS
  12. CHAPTER 4. The Syntheses of 3- and 4-Deoxy-hexoses
  13. CHAPTER 5. RECENT DEVELOPMENTS IN THE SYNTHESIS OF POLYSACCHARIDES AND STEREOSPECSFICITY OF GLYCOSYLATION REACTIONS
  14. CHAPTER 6. LEVOGLUCOSENONE: A VERSATILE CARBOHYDRATE PRECURSOR FOR THE SYNTHESIS OF NATURAL PRODUCTS
  15. CHAPTER 7. Chemical Synthesis of Branched Oligoribonucleotides and their Related Compounds
  16. CHAPTER 8. Oxidation Products of Guaiazulene and Other Azulenic Hydrocarbons
  17. CHAPTER 9. Syntheses of Hydroazulene Sesquiterpenes via Rearrangement of Substituted Hydronaphthalene Precursors
  18. CHAPTER 10. A CHAPTER IN THUJONE CHEMISTRY - FROM WASTE BY-PRODUCT TO NATURAL PRODUCTS ANDRELATED COMPOUNDS
  19. CHAPTER 11. The Total Synthesis of Eudesm-11-en-4-ols
  20. CHAPTER 12. Asymmetric Synthesis Using Chiral Acetals from C2-Symmetric Diols and Its Application to Natural Product Synthesis
  21. CHAPTER 13. ASYMMETRIC SYNTHESIS OF SOME NATURAL SPIRO COMPOUNDS UTILIZING CHIRAL SULFOXIDE AUXILIARY
  22. CHAPTER 14. ASYMMETRIC CONSTRUCTION OF VERSATILE CHIRAL BUILDING BLOCKS AND THEIR APPLICATION TO THE SYNTHESES OF NATURAL PRODUCTS
  23. CHAPTER 15. CATIONIC CYCLOPENTANNELATION REACTIONS
  24. CHAPTER 16. CHIRAL CONSTRUCTION OF QUATERNARY CARBONS THROUGH ADDITION-ELIMINATION PROCESS: APPLICATION TO THE NATURAL PRODUCT SYNTHESES
  25. CHAPTER 17. ORGANIC SYNTHESIS USING HYDROGEN ATOM ABSTRACTION REACTIONS GEORGE A. KRAUS and MARK D. SCHWINDEN
  26. CHAPTER 18. TAXODIONE SYN'GHE'G1C STUDIES
  27. CHAPTER 19. SYNTHETIC STUDIES IN THE FIELD OF INDOLE ALKALOIDS. PART 2.
  28. CHAPTER 20. STEREOSELECTIVITY IN SYNTHESIS AND BIOSYNTHESIS OF LUPINE AND NITRARIA ALKALOIDS
  29. CHAPTER 21. BIOMIMETIC SYNTHESIS OF BENZO[C]PHENANTHRIDINE ALKALOIDS FROM PROTOBERBERINES
  30. CHAPTER 22. SYNTHETIC APPROACHES TO VINBLASTINE AND VINCRISTINE - ANTICANCER ALKALOIDS OF CATHARANTHUS ROSEUS
  31. SUBJECT INDEX