Breast Cancer

Focusing Tumor Microenvironment, Stem cells and Metastasis

Mehmet Gunduz, Esra Gunduz, Mehmet Gunduz, Esra Gunduz

• Publisher: IntechOpen
• Year: 2011
• Print ISBN:
  9789533077666
• eBook ISBN:
  9789535166047
• Topic: Medicine
• Subtopic: Rheumatology, Orthopedics & Prosthetics

Cancer is the leading cause of death in most countries and its consequences result in huge economic, social and psychological burden. Breast cancer is the most frequently diagnosed cancer type and the leading cause of cancer death among females. In this book, we discussed characteristics of breast cancer cell, role of microenvironment, stem cells and metastasis for this deadly cancer. We hope that this book will contribute to the development of novel diagnostic as well as therapeutic approaches.

Table of contents

• Breast Cancer - Focusing Tumor Microenvironment, Stem cells and Metastasis
• Contents
• Preface
• Part 1 Breast Cancer Cell Lines, Tumor Classification, In Vitro Cancer Models
• Part 2 Breast Cancer and Microenvironment
• Part 3 Breast Cancer Stem Cells
• Part 4 Breast Cancer Gene Regulation
• Part 5 Breast Cancer Cell Interaction, Invasion and Metastasis
• Chapter 18 - The Mesenchymal-Like Phenotype of the MDA-MB-231 Cell Line
• Chapter 19 - p130Cas and p140Cap as the Bad and Good Guys in Breast Cancer Cell Progression to an Invasive Phenotype
• 20. Fibrillar Human Serum Albumin Suppresses Breast Cancer Cell Growth and Metastasis
• Chapter 21. On the Role of Cell Surface Chondroitin Sulfates and Their Core Proteinsin Breast Cancer Metastasis
• Chapter 22. Endocrine Resistance and Epithelial Mesenchymal Transition in Breast Cancer
• 23. Junctional Adhesion Molecules (JAMs - New Players in Breast Cancer?
• 24. Breast Cancer Metastasis: Advances Through the Use of In Vitro Co-Culture Model Systems
• 25. Breast Cancer Metastases to Bone: Role of the Microenvironment
• 26. Rho GTPases and Breast Cancer