
- 150 pages
- English
- PDF
- Available on iOS & Android
Anticoagulation Therapy
About this book
The available parenteral and oral anticoagulants have a large clinical use. Understanding biochemistry of anticoagulants may help to improve therapeutic strategies. Resistance to vitamin K antagonist drugs might be a problem for rodent populations. Patients who have thrombogenic risk factors should be anticoagulated. The need for cardiac implantable electronic devices is increasing, and there is a substantial number of patients who are on oral anticoagulant therapy. Prothrombin complex concentrate and other plasma concentrates are useful to deal with over-coagulated situations. The efficacy and safety of non-vitamin K antagonist oral anticoagulants have been proven in large phase III trials. The real-world data suggest even better outcomes with these agents compared to vitamin K antagonists.
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Table of contents
- Anticoagulation Therapy
- Contents
- Preface
- Chapter 1 Biochemistry and Stereochemistry of Anticoagulants
- Chapter 2 Comparative Biology of the Resistance to Vitamin K Antagonists: An Overview of the Resistance Mechanisms
- Chapter 3 The Risk Factors of Thrombogenic, Thrombophilia, and the Principle for Heparin Prophylaxis in Personalized Medicine
- Chapter 4 Management of Anticoagulation Around Cardiac Implantable Electronic Device Surgery
- Chapter 5 Prothrombin Complex Concentrate, a General Antidote for Oral Anticoagulation
- Chapter 6 Non-Vitamin K Antagonist Oral Anticoagulants in Atrial Fibrillation: Pharmacology and Phase III Clinical Trials
- Chapter 7 Non–Vitamin K Antagonist Oral Anticoagulants, Clinical Use, Real-World Data, and Reversal of Anticoagulant Effect