Exploring New Findings on Amyloidosis
eBook - PDF

Exploring New Findings on Amyloidosis

  1. 348 pages
  2. English
  3. PDF
  4. Available on iOS & Android
eBook - PDF

Exploring New Findings on Amyloidosis

About this book

Amyloid protein aggregates are involved in ''protein-misfolding diseases'' of enormous social and economic impact, still with no effective therapies. The most prevalent amyloid pathologies are related to neurodegenerative diseases, but amyloidosis also affects other organs. The majority of the studies includes serious health connotations on amyloids. However, not all amyloid fibers play a detrimental role in host. An increasing number of studies shows an important beneficial role as ''functional amyloids''. This book opens an exciting door to provide up-to-date information about the function and the mechanisms of the amyloid formation process from the structural, biophysical, biomedical, and nanotechnological perspective, combining the new findings on toxic and functional amyloids studies using theoretical and experimental approaches to fight against amyloid-based diseases.

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Information

Publisher
IntechOpen
Year
2016
Print ISBN
9789535126188
eBook ISBN
9789535154471
Topic
Medicine
Subtopic
Cardiology

Table of contents

  1. Exploring New Findings on Amyloidosis
  2. Contents
  3. Preface
  4. Chapter 1 Modulating Role of TTR in Aβ Toxicity, from Health to Disease
  5. Chapter 2 Supramolecular Organization of Amyloid Fibrils
  6. Chapter 3 Advances in AFM Imaging Applications for Characterizing the Biophysical Properties of Amyloid Fibrils
  7. Chapter 4 Effects of Amyloid-β Deposition on Mitochondrial Complex I Activity in Brain: A PET Study in Monkeys
  8. Chapter 5 Kinetics of Amyloid Formation by Different Proteins and Peptides: Polymorphism and Sizes of Folding Nuclei of Fibrils
  9. Chapter 6 Role of Glycation in Amyloid: Effect on the Aggregation Process and Cytotoxicity
  10. Chapter 7 Is Alzheimer's Associated Amyloid Beta an Innate Immune Protein
  11. Chapter 8 Amyloidogenesis and Responses to Stress
  12. Chapter 9 Developments in the Treatment of Amyloid A Amyloidosis Secondary to Rheumatoid Arthritis
  13. Chapter 10 The Role of Human IAPP in Stress and Inflammatory Processes in Type 2 Diabetes
  14. Chapter 11 Proteasome Inhibitors to Treat AL Amyloidosis
  15. Chapter 12 Amyloid Nephropathy: A Practical Diagnostic Approach and Review on Pathogenesis
  16. Chapter 13 A Nanobody‐Based Approach to Amyloid Diseases, the Gelsolin Case Study

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Yes, you can access Exploring New Findings on Amyloidosis by Ana-Maria Fernandez-Escamilla in PDF and/or ePUB format, as well as other popular books in Medicine & Cardiology. We have over 1.5 million books available in our catalogue for you to explore.