
- 160 pages
- English
- PDF
- Available on iOS & Android
New Insights into Systemic Sclerosis
About this book
Systemic sclerosis (scleroderma) is an incurable connective tissue disease of unknown etiology. Three key processes play a pivotal role in the pathogenesis: immune dysregulation and inflammation, endothelial injury and vasculopathy, and fibrosis. Tissue fibrosis is the dominant and characteristic feature that affects the skin and visceral organs. Life expectancy of scleroderma patients has improved over recent years, mainly because of better treatment of organ involvement and complications; however, no curative disease-modifying therapies exist to date. This book aims to provide students, trainees, rheumatologists, and other specialists interested in this disease with a comprehensive overview of novel pathogenetic mechanisms, management approaches, and therapeutic targets of several major vascular and fibrotic manifestations, and is useful insight into a number of usually neglected aspects of scleroderma.
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Table of contents
- New Insights into Systemic Sclerosis
- Contents
- Preface
- Chapter1 Advances in Management of Pulmonary Hypertension Associated with Systemic Sclerosis
- Chapter2 Renal Involvement in Systemic Sclerosis
- Chapter3 Gastrointestinal Involvement in Systemic Sclerosis: Overview, Neglected Aspects, Malnutrition, Body Composition and Management
- Chapter4 Systemic Sclerosis Mimics
- Chapter5 Sexual Dysfunction in Patients with Systemic Scleros
- Chapter6 Biopsychosocial Aspects in Management of Scleroderma