Drug Transporters
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Drug Transporters

Molecular Characterization and Role in Drug Disposition

Guofeng You, Marilyn E. Morris, Binghe Wang, Guofeng You, Marilyn E. Morris

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eBook - PDF
No longer available |Learn more

Drug Transporters

Molecular Characterization and Role in Drug Disposition

Guofeng You, Marilyn E. Morris, Binghe Wang, Guofeng You, Marilyn E. Morris

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About This Book

This new edition overviews drug transporters and presents the principles of drug transport and associated techniques, featuring new chapters on multidrug and toxin extrusion proteins, placental transport, in silico approaches in drug discovery, and regulatory guidance for drug transport studies in drug development.

•Describes drug transporter families, mechanisms, and clinical implications along with experimental methods for studying and characterizing drug transporters
•Includes new chapters on multidrug and toxin extrusion proteins, placental transport and in silico approaches in drug discovery
•Has a new chapter covering regulatory guidance for the evaluation of drug transport in drug development with global criteria used for drug transporters in clinical trials
•Arranges material to go from fundamental mechanisms to clinical outcomes, making the book useful for novice and expert readers

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Information

Publisher
Wiley
Year
2014
ISBN
9781118705049
Edition
2
Subtopic
Pharmacology

Table of contents