
Genetic Analysis of Complex Disease
- English
- PDF
- Available on iOS & Android
Genetic Analysis of Complex Disease
About this book
An up-to-date and complete treatment of the strategies, designs and analysis methods for studying complex genetic disease in human beings
In the newly revised Third Edition of Genetic Analysis of Complex Diseases, a team of distinguished geneticists delivers a comprehensive introduction to the most relevant strategies, designs and methods of analysis for the study of complex genetic disease in humans. The book focuses on concepts and designs, thereby offering readers a broad understanding of common problems and solutions in the field based on successful applications in the design and execution of genetic studies.
This edited volume contains contributions from some of the leading voices in the area and presents new chapters on high-throughput genomic sequencing, copy-number variant analysis and epigenetic studies. Providing clear and easily referenced overviews of the considerations involved in genetic analysis of complex human genetic disease, including sampling, design, data collection, linkage and association studies and social, legal and ethical issues.
Genetic Analysis of Complex Diseases also provides:
- A thorough introduction to study design for the identification of genes in complex traits
- Comprehensive explorations of basic concepts in genetics, disease phenotype definition and the determination of the genetic components of disease
- Practical discussions of modern bioinformatics tools for analysis of genetic data
- Reflecting on responsible conduct of research in genetic studies, as well as linkage analysis and data management
- New expanded chapter on complex genetic interactions
This latest edition of Genetic Analysis of Complex Diseases is a must-read resource for molecular biologists, human geneticists, genetic epidemiologists and pharmaceutical researchers. It is also invaluable for graduate students taking courses in statistical genetics or genetic epidemiology.
Frequently asked questions
- Essential is ideal for learners and professionals who enjoy exploring a wide range of subjects. Access the Essential Library with 800,000+ trusted titles and best-sellers across business, personal growth, and the humanities. Includes unlimited reading time and Standard Read Aloud voice.
- Complete: Perfect for advanced learners and researchers needing full, unrestricted access. Unlock 1.4M+ books across hundreds of subjects, including academic and specialized titles. The Complete Plan also includes advanced features like Premium Read Aloud and Research Assistant.
Please note we cannot support devices running on iOS 13 and Android 7 or earlier. Learn more about using the app.
Information
Table of contents
- Cover
- Title Page
- Copyright Page
- Contents
- List of Contributors
- Foreword
- Chapter 1 Designing a Study for Identifying Genes in Complex Traits
- Chapter 2 Basic Concepts in Genetics
- Chapter 3 Determining the Genetic Component of a Disease
- Chapter 4 Study Design for Genetic Studies
- Chapter 5 Responsible Conduct of Research in Genetic Studies
- Chapter 6 Linkage Analysis
- Chapter 7 Data Management
- Chapter 8 Linkage Disequilibrium and Association Analysis
- Chapter 9 Genome-Wide Association Studies
- Chapter 10 Bioinformatics of Human Genetic Disease Studies
- Chapter 11 Complex Genetic Interactions/Data Mining/Dimensionality Reduction
- Chapter 12 Sample Size, Power, and Data Simulation
- Index
- EULA