Genetic Analysis of Complex Disease
eBook - PDF

Genetic Analysis of Complex Disease

  1. English
  2. PDF
  3. Available on iOS & Android
eBook - PDF

About this book

Genetic Analysis of Complex Diseases

An up-to-date and complete treatment of the strategies, designs and analysis methods for studying complex genetic disease in human beings

In the newly revised Third Edition of Genetic Analysis of Complex Diseases, a team of distinguished geneticists delivers a comprehensive introduction to the most relevant strategies, designs and methods of analysis for the study of complex genetic disease in humans. The book focuses on concepts and designs, thereby offering readers a broad understanding of common problems and solutions in the field based on successful applications in the design and execution of genetic studies.

This edited volume contains contributions from some of the leading voices in the area and presents new chapters on high-throughput genomic sequencing, copy-number variant analysis and epigenetic studies. Providing clear and easily referenced overviews of the considerations involved in genetic analysis of complex human genetic disease, including sampling, design, data collection, linkage and association studies and social, legal and ethical issues.

Genetic Analysis of Complex Diseases also provides:

  • A thorough introduction to study design for the identification of genes in complex traits
  • Comprehensive explorations of basic concepts in genetics, disease phenotype definition and the determination of the genetic components of disease
  • Practical discussions of modern bioinformatics tools for analysis of genetic data
  • Reflecting on responsible conduct of research in genetic studies, as well as linkage analysis and data management
  • New expanded chapter on complex genetic interactions

This latest edition of Genetic Analysis of Complex Diseases is a must-read resource for molecular biologists, human geneticists, genetic epidemiologists and pharmaceutical researchers. It is also invaluable for graduate students taking courses in statistical genetics or genetic epidemiology.

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Yes, you can access Genetic Analysis of Complex Disease by William K. Scott, Marylyn D. Ritchie, William K. Scott,Marylyn D. Ritchie in PDF and/or ePUB format, as well as other popular books in Biological Sciences & Genetics & Genomics. We have over one million books available in our catalogue for you to explore.

Information

Table of contents

  1. Cover
  2. Title Page
  3. Copyright Page
  4. Contents
  5. List of Contributors
  6. Foreword
  7. Chapter 1 Designing a Study for Identifying Genes in Complex Traits
  8. Chapter 2 Basic Concepts in Genetics
  9. Chapter 3 Determining the Genetic Component of a Disease
  10. Chapter 4 Study Design for Genetic Studies
  11. Chapter 5 Responsible Conduct of Research in Genetic Studies
  12. Chapter 6 Linkage Analysis
  13. Chapter 7 Data Management
  14. Chapter 8 Linkage Disequilibrium and Association Analysis
  15. Chapter 9 Genome-Wide Association Studies
  16. Chapter 10 Bioinformatics of Human Genetic Disease Studies
  17. Chapter 11 Complex Genetic Interactions/Data Mining/Dimensionality Reduction
  18. Chapter 12 Sample Size, Power, and Data Simulation
  19. Index
  20. EULA