Rapid catalyst screening for enantioselective Diels-Alder reactions was accomplished by mass spectrometric monitoring of reaction intermediates of the retro-Diels-Alder reaction. Copper catalysts as well as metal-free organocatalysts were tested. Furthermore, a protocol for simultaneous screening of catalyst mixtures was developed, offering new possibilities for high-throughput catalyst development.

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9783867274456
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1Table of contents
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