Nurses play a vital role in any healthcare setting and cover the largest workforce; they act as direct care providers who serve patients twenty-four hours a day, seven days a week. This gives nurses a unique view on both patient care and hospital services. The workplace stress is normal. While, excessive stress can interfere with productivity, performance and affects the physical and the emotional health. Often, the ability to cope with stress can mean the difference between success and failure at work. Also, Collaboration between nurses and physicians is linked to positive outcomes for patients, especially in psychiatric units. However, effective collaboration poses challenges as work stressors. So, effective work stressors coping strategies have the high concern from organization management as a method for maintaining a high level of collaboration.