The book "Cross Cultural Ethno-Medicinal Practices in Southern Assam: A Comparative Study" is the documentation of research works and deals with the plant resources of southern part of Assam, India, which is universally recognized as one of the unique ventures of biodiversity.A number of ethnic groups with their indigenous inhabitants are well aware about the medicinal properties of plant growing through their surroundings. The tribal habitats of the Southern Assam region display remarkable diversity in their life forms, culture, language and traditional beliefs in uses of medicinal plants.The dependency on numerous traditional practices provide sufficient basis to accept the folklore herbal medicine in their traditional system.This study was carried out and completed with field works and literature survey centering seven specific tribes viz., Barman, Chorei, Hmar, Jaintia, Kuki, Raungmei Naga & Reang of Southern Assam. The book will definitely serve as a comprehensive reference tool for the ethno-botanical studies for the future research area by providing a valuable source with the selection of different medicinal plants in a particular region among the different communities.