Oral mucous membrane is an excellent indicator of the constitutional state of the patient. Oral mucosa is normally under trophic influences of various hormones. Many studies have shown that oral mucosa is sensitive to effects of hormones, as their levels change during various phases. Lesions like oral ulcers, increased gingival bleeding, periodontitis, candida infection could be related to hormone turnover and therefore treated accordingly. Oral health is an integral component of general health and well-being of an individual. Knowledge about the link between oral disease and systemic health is growing rapidly. Hormonal fluctuations have a great effect on the oral health. Oral health care professionals should be aware of the importance of recognizing oral manifestations of systemic diseases. The dentist plays a fundamental role in the early diagnosis knowing that the first symptoms of the disease occur in the oral cavity with normal or show subtle changes in initial laboratory tests. This book provides detailed explanation on oral manifestations acting as self-sufficient guide for all dental practitioners.