Heterocycles are a central component in natural product chemistry, pharmaceuticals, agrochemicals, and material science. New synthetic methodologies integrating the sequencing of multicomponent reactions (MCRs) are today being used for the rapid synthesis of diversified heterocycles in just one step. Multicomponent Reactions towards Heterocycles presents an up-to-date summary MCR chemistry with a focus on the conjugation between modern synthetic methodologies and MCRs.

Featuring contributions by leaders in the field, this comprehensive resource highlights applications of MCRs in natural products and intermediate synthesis, discusses current trends and future prospects in MCR chemistry, outlines novel multicomponent procedures, and more. The authors provide the practical information required for designing new reaction strategies and mechanisms, covering topics including MCR-based green synthetic methods, cyclization and cycloaddition reactions, heterocycle multicomponent syntheses in a continuous flow, catalytic alkynoyl generation, MCR synthesis of saturated heterocycles, and C–H functionalization and multicomponent reactions.

Provides a thorough overview of heterocycles as input in multicomponent reactions
Discusses recent advances in the field of MCR chemistry and progress in the synthesis and functionalization of heterocycles
Demonstrates the use of MCRs to simplify synthetic design and achieve complexity and diversity in novel bioactive molecules
Highlights examples of multicomponent polymerizations, target-oriented synthesis, and applications of MCR in medicinal chemistry
Explains the methodology of using on-resin MCRs to produce heterocycle compounds

Illustrating the key role of MCRs towards heterocycles in natural product synthesis, drug discovery, organic synthesis, and other applications, Multicomponent Reactions towards Heterocycles is required reading for synthetic chemists in academia and industry alike.

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Yes, you can access Multicomponent Reactions towards Heterocycles by Erik Van der Eycken, Upendra K. Sharma, Erik Van der Eycken,Upendra K. Sharma in PDF and/or ePUB format, as well as other popular books in Physical Sciences & Physical & Theoretical Chemistry. We have over one million books available in our catalogue for you to explore.

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Physical Sciences

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Physical & Theoretical Chemistry

Cover
Title Page
Copyright
Contents
Preface
Chapter 1 Heterocycles as Inputs in MCRs: An Update
Chapter 2 Heterocycles and Multicomponent Polymerizations
Chapter 3 Multicomponent Reactions in Medicinal Chemistry
Chapter 4 Solid‐Phase Heterocycle Synthesis Using Multicomponent Reactions
Chapter 5 Green Synthesis of Heterocycles Via MCRs
Chapter 6 The Use of Flow Chemistry in the Multicomponent Synthesis of Heterocycles
Chapter 7 C–H Functionalization as an Imperative Tool Toward Multicomponent Synthesis and Modification of Heterocycles
Chapter 8 Multicomponent‐Switched Reactions in Synthesis of Heterocycles
Chapter 9 Recent Applications of Multicomponent Reactions Toward Heterocyclic Drug Discovery
Chapter 10 Multicomponent Syntheses of Heterocycles by Catalytic Generation of Alkynoyl Intermediates
Chapter 11 Synthesis of Saturated Heterocycles via Multicomponent Reactions
Chapter 12 Multicomponent Reactions and Asymmetric Catalysis
Chapter 13 Recent Trends in Metal‐catalyzed MCRs Toward Heterocycles
Index
EULA

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