Biochemistry of Drug Metabolizing Enzymes
eBook - ePub

Biochemistry of Drug Metabolizing Enzymes

Trends and Challenges

  1. 586 pages
  2. English
  3. ePUB (mobile friendly)
  4. Available on iOS & Android
eBook - ePub

Biochemistry of Drug Metabolizing Enzymes

Trends and Challenges

About this book

Biochemistry of Drug Metabolizing Enzymes: Trends and Challenges is a complete and well-integrated reference on their mechanisms of action, their role in diseases, agents responsible for their deactivation, and their malfunction. Chapters explain the biochemistry of DMEs, including biochemical activation, functions, computational approaches, different contaminants on the action and function of DMEs, and describe the importance of DMEs in the drug development process. Conditions covered include metabolic diseases, cardiovascular diseases, neurological diseases, physiological diseases, xenobiotics and inflammatory responses, and their contribution in the malfunctioning of drug metabolizing enzymes. This book is the perfect resource for pharmacology and biochemistry researchers to understand the principles of DMEs. Researchers in the corporate environment will also benefit from the comprehensive list of diseases associated with malfunction of DMEs. - Includes extensive classification of DMEs, their mechanism of action and computational analysis - Covers the biotransformation of drug by DMEs and the possible impact of environmental contaminants - Discusses the activity of DMEs in different clinical conditions such as cardiovascular disease, metabolic disorders, inflammation and neurotoxicity - Includes modern and novel bioanalytical techniques to predict the effect of DMEs

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Yes, you can access Biochemistry of Drug Metabolizing Enzymes by Muhammad Sajid Hamid Akash,Kanwal Rehman in PDF and/or ePUB format, as well as other popular books in Medicine & Pharmacology. We have over one million books available in our catalogue for you to explore.

Information

Publisher
Academic Press
Year
2022
Print ISBN
9780323951203
eBook ISBN
9780323951210
Topic
Medicine
Subtopic
Pharmacology

Table of contents

  1. Biochemistry of Drug Metabolizing Enzymes
  2. Chapter 1 Biochemical activation and functions of drug-metabolizing enzymes
  3. Chapter 2 Computational approaches for drug-metabolizing enzymes: Concepts and challenges
  4. Chapter 3 Role of drug-metabolizing enzymes in biotransformation of drugs
  5. Chapter 4 Emerging environmental contaminants and drug-metabolizing enzymes
  6. Chapter 5 Drug-metabolizing enzymes and fate of prodrugs: From function to regulation
  7. Chapter 6 Hormones and drug-metabolizing enzymes: From function to regulation
  8. Chapter 7 Receptors and drug-metabolizing enzymes: From function to regulation
  9. Chapter 8 Biochemistry of cathepsins enzymes and their metabolic activity in the lysosome
  10. Chapter 9 Fate of drug-metabolizing enzymes in metabolic diseases
  11. Chapter 10 Fate of drug-metabolizing enzymes in cardiovascular diseases: Concepts and challenges
  12. Chapter 11 Fate of drug-metabolizing enzymes in neurological diseases: Challenges and strategies
  13. Chapter 12 Impact of physiological factors on drug-metabolizing enzymes: From function to regulation
  14. Chapter 13 Xenobiotics and drug-metabolizing enzymes: Challenges and strategies
  15. Chapter 14 Drug-metabolizing enzymes and inflammatory responses
  16. Chapter 15 Polymorphisms in drug-metabolizing enzymes: Challenges and strategies
  17. Chapter 16 Modulation of human microbiome and drug metabolism
  18. Chapter 17 Bioanalytical techniques for prediction of metabolic activity of drug-metabolizing enzymes
  19. Chapter 18 Role of pharmacogenomics for prediction of personalized medicines
  20. Chapter 19 Dietary sources of drug-metabolizing enzymes: From production to regulation
  21. Chapter 20 Vitamin deficiencies and drug-metabolizing enzymes: Challenges and strategies
  22. Chapter 21 Fate of drug-metabolizing enzymes in malnutrition: Challenges and strategies
  23. Chapter 22 Drug-metabolizing enzymes and oxidative stress
  24. Index