
Characterization, regulation, and interactions within the protease web
- 428 pages
- English
- PDF
- Available on iOS & Android
Characterization, regulation, and interactions within the protease web
About this book
This handbook is the first comprehensive book of its kind reviewing the clinically relevant current status of tissue kallikrein and kallikrein-related peptidases research. Since several members of the KLK family are key players in (patho-)physiological processes, structural, functional, and regulatory studies are under way to develop new strategies to prevent and treat disorders to which individual members of the KLK protease family contribute significantly. The goal of this book is to inform clinicians, physician scientists and researchers about the prominent role of the multifaceted and interactive KLK system in normal physiology and pathological organ function.
Trusted by 375,005 students
Access to over 1 million titles for a fair monthly price.
Study more efficiently using our study tools.
Information
Table of contents
- Preface
- List of contributing authors
- Table of Contents
- Introduction to Volume 1: Kallikrein-related Peptidases. Characterization, Regulation, and Interactions Within the Protease We
- 1 Genomic Structure of the KLK Locus
- 2 Single Nucleotide Polymorphisms in the Human KLK Locus and Their Implication in Various Diseases
- 3 Evolution of Kallikrein-related Peptidases
- 4 Structural Aspects of Kallikrein-related Peptidases
- 5 Molecular Recognition Properties of Kallikrein-related Peptidases on Synthetic and Endogenous Substrates
- 6 Natural, Engineered and Synthetic Inhibitors of Kallikrein-related Peptidases
- 7 Kallikrein-related Peptidases as Pharmaceutical Targets
- 8 Expression of Kallikrein-related Peptidases under (Patho-)Physiological Conditions
- 9 Kallikrein-related Peptidases within the Proteolytic Web
- 10 Kallikrein-Kinin Cascade: Bioregulation by Human Tissue Kallikrein 1 (hK1, KLK1)
- 11 Role of KLK4 in Dental Enamel Formation
- 12 Kallikrein-related Peptidases and Semen
- 13 Kallikrein-related Peptidases and Inhibitors of the Skin
- 14 Physiological and Pathophysiological Roles of Kallikrein-related Peptidases in the Central Nervous System
- 15 Kallikrein-related Peptidases (KLKs), Proteinase-mediated Signaling and Proteinase-activated receptors (PARs)
- Index
Frequently asked questions
- Essential is ideal for learners and professionals who enjoy exploring a wide range of subjects. Access the Essential Library with 800,000+ trusted titles and best-sellers across business, personal growth, and the humanities. Includes unlimited reading time and Standard Read Aloud voice.
- Complete: Perfect for advanced learners and researchers needing full, unrestricted access. Unlock 1.4M+ books across hundreds of subjects, including academic and specialized titles. The Complete Plan also includes advanced features like Premium Read Aloud and Research Assistant.
Please note we cannot support devices running on iOS 13 and Android 7 or earlier. Learn more about using the app