Volume 24, entitled Targeted Metallo-Drugs: Design, Development, and Modes of Action, of the series Metal Ions in Life Sciences (MILS), fosters inter-disciplinary research in the vibrant field of Biological Inorganic Chemistry. Inspired by the clinical success of cisplatin as a leading anticancer drug but mindful of the shortcomings associated with its use including dose-limiting toxic side effects and acquired or intrinsic drug resistance, scientists across the globe have been endeavoring to identify new metallo-drugs for therapeutic exploitation. This has led to innovative metallo-drug candidates that (i) enhance cancer cell selectivity, thus reducing toxic side effects, and/or (ii) possess new modes of action to improve efficacy and also target resistance pathways. This and more are captured in MILS- 24 which consists of 12 comprehensive, well-illustrated, and up to date chapters with over 1600 citations, 100 figures, and 10 tables with key contributions from 32 international experts from Europe, Asia, and North and South America. MILS- 24 not only keeps the scientific community abreast of latest developments, it also serves as an invaluable resource to stimulate further research on targeted metallo-drug design and development.

It covers anticancer, antimicrobial, antiviral, and other agents, such as those targeting tropical diseases and cyanide poisoning and radiometals in molecular imaging and therapy
It highlights recent metallo-drug developments targeting COVID-19
It features advanced spectroscopic methods and metallomics as important tools to elucidate the modes of actions of metallo-drugs

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Yes, you can access Targeted Metallo-Drugs by Etelka Farkas, Celine J. Marmion, Etelka Farkas,Celine J. Marmion in PDF and/or ePUB format, as well as other popular books in Medicina & Farmacología. We have over one million books available in our catalogue for you to explore.

Information

Publisher

Year

Print ISBN

eBook ISBN

Edition

Topic

Medicina

Subtopic

Farmacología

Cover
Title Page
Copyright Page
About the Editors
Historical Development and Perspectives of the Series
Preface to Volume 24
Table of Contents
Contributors to Volume 24
Handbooks and Book Series Published and (Co-)edited by the SIGELs
Chapter 1 Metal-Based Prodrugs Activated by Cancer-Specific Stimuli
Chapter 2 Light-Activated Drugs for Photodynamic and Photoactivated Therapy
Chapter 3 Mitochondria as a Metallo-Drug Target for Therapeutic Purposes
Chapter 4 Transition Metal-Based Antiviral Agents Against SARS-CoV-2 and Other Pathogenic Viruses
Chapter 5 Exploiting the Chemical Diversity of Metal Compounds as a Source of Novel Anti-COVID-19 Drugs
Chapter 6 Evaluating the Potential of Novel Metal-Based Drugs for Treating Drug-Resistant Bacteria
Chapter 7 Prospective Metallo-Drugs Including Bioactive Compounds Selection of Co-Ligands to Tune Biological Activity Against Neglected Tropical Diseases
Chapter 8 Challenges in Targeting Cyanide Poisoning: Advantages in Exploiting Metal Complexes in Its Treatment
Chapter 9 Advanced Microscopy Methods for Elucidating the Localization of Metal Complexes in Cancer Cells
Chapter 10 Metalloproteomics: A Powerful Technique for Metals in Medicine
Chapter 11 Metal-Based Nanoclusters for Biomedical Applications
Chapter 12 Radiometals in Molecular Imaging and Therapy
Index

About this book

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Table of contents