Cancer is a major killer all over the world. Even with all the progress made, chemotherapy is still the mainstay of modern cancer treatment. The progression of the cellular defeat of numerous independent anticancer drugs in terms of their chemical structure is a major barrier to successful chemotherapy. Multi-drug resistance (MDR) is a term for the fact that most cancer patients exhibit this phenomenon. According to the numbers, drug resistance carries the blame for 90% of cancer patient deaths. Refractory cancer and tumor recurrence are common outcomes of prolonged chemotherapy. Because of the prevalence of drug-resistance mutations, the difficulty of treating tumors increases and the therapeutic efficacy of drugs decreases.

Multi-Drug Resistance in Cancer: Mechanism and Treatment Strategies contains nine chapters that cover topics such as: studying the mechanics of resistance to drugs by autophagy; studies to delineate the role of efflux transporters; expression of drug transporters; resistance to targeted therapies in breast cancer; advances in metallodrug driven combination treatment for cancer; and use of natural agents for the overcoming of cancer drug resistance.

The book aims to provide the latest data on the mechanisms of cellular resistance to anticancer agents currently used in clinical treatment. It provides a better understanding of the mechanisms of MDR and targets of novel chemotherapy agents which should guide future research concerning new effective strategies in cancer treatment.

Audience

This book is written for pharmaceutical and biomedical scientists and researchers at both the bench and in the clinic who are interested in the mechanisms and strategies for overcoming cancer's multi-drug resistance.

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Yes, you can access Multi-Drug Resistance in Cancer by Rishabha Malviya,Arun Kumar Singh,Deepika Yadav in PDF and/or ePUB format, as well as other popular books in Medicina & Farmacologia. We have over one million books available in our catalogue for you to explore.

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Publisher

Year

Print ISBN

eBook ISBN

Edition

Topic

Medicina

Subtopic

Farmacologia

Cover
Title Page
Copyright Page
Contents
Foreword
Preface
Acknowledgment
Chapter 1 Multi-Drug Rmesistance in Cancer: Understanding of Treatment Strategies
Chapter 2 Understanding Different Mechanisms Involved in Cancer Drug Resistance: Proposing Novel Strategies to Overcome MDR
Chapter 3 Molecular Mechanism of Multi-Drug Resistant Cancer Cells
Chapter 4 Natural Products for Clinical Management of Drug Resistant Cancer Cells
Chapter 5 Understanding of Autophagy to Combat MDR During Anticancer Therapy
Chapter 6 Transporter Inhibitors: A Chemotherapeutic Regimen to Improve the Clinical Outcome of Colorectal Cancer
Chapter 7 Epithelial to Mesenchymal Transition (EMT): Major Contribution to Cancer Drug Therapy Resistance
Chapter 8 Advances in Metallodrug-Driven Combination Therapy for Treatment of Cancer
Chapter 9 Novel Strategies Preventing Emergence of MDR in Breast Cancer
Index
EULA

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Table of contents