Paternal Influences on Human Reproductive Success
eBook - PDF

Paternal Influences on Human Reproductive Success

  1. English
  2. PDF
  3. Available on iOS & Android
eBook - PDF

Paternal Influences on Human Reproductive Success

About this book

Historically, sperm have been seen as simply a mechanism of transferring a haploid set of chromosomes to the oocyte. However, data from assisted reproduction therapies (ART) have demonstrated that in many couples the sperm appears to be responsible for abnormal embryogenesis. Recent advances in genetic and epigenetic techniques have identified key mechanisms by which the sperm, and the DNA carried by the sperm, can affect early embryonic development. Paternal Influences on Human Reproductive Success examines the genetic and epigenetic influences on embryogenesis, as well as practical clinical factors related to the male contribution to reproductive success. It also provides 'cutting edge' data and analysis of recent evaluations of the role of advanced paternal age, environmental influences and lifestyle factors on male reproductive fitness, making this an invaluable text for physicians treating patients for infertility, recurrent pregnancy loss, and developmental anomalies, as well as basic scientists studying embryogenesis and spermatogenesis.

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Yes, you can access Paternal Influences on Human Reproductive Success by Douglas T. Carrell in PDF and/or ePUB format, as well as other popular books in Medicine & Gynecology, Obstetrics & Midwifery. We have over one million books available in our catalogue for you to explore.

Table of contents

  1. Cover
  2. Contents
  3. Contributors
  4. Preface
  5. Chapter 1 The reproductive fitness of the human male gamete
  6. Chapter 2 The sperm genome: effect of aneuploidies, structural variations, single nucleotide changes, and DNA damage on embryogenesis and development
  7. Chapter 3 The sperm epigenome: a role in embryogenesis and fetal health?
  8. Chapter 4 Imprinted gene anomalies in sperm
  9. Chapter 5 Has the renewed interest in sperm RNA led to fresh insights? A critical review and hypothesis
  10. Chapter 6 The role of the sperm centrosome in reproductive fitness
  11. Chapter 7 The male biological clock
  12. Chapter 8 The role of aging on fecundity in the male
  13. Chapter 9 Aging, DNA damage, and reproductive outcome
  14. Chapter 10 Paternal aging and increased risk of congenital disease, psychiatric disorders, and cancer
  15. Chapter 11 Sexual function in the aging male
  16. Chapter 12 Supplements and replacement therapies for the aging male and their effects on reproductive fitness
  17. Chapter 13 Environment and lifestyle effects on fertility
  18. Chapter 14 Obesity and male infertility: is there an effect on embryogenesis?
  19. Chapter 15 Intracytoplasmic sperm injection: does the sperm matter?
  20. Chapter 16 Sperm selection and ART outcome: a means to overcome the effects of aging and abnormal spermatogenesis?
  21. Chapter 17 Variability of human semen quality: caution in interpreting semen analysis data
  22. Chapter 18 Semen characteristics and aging: technical considerations regarding variability
  23. Index