The Genetics of African Populations in Health and Disease
eBook - PDF

The Genetics of African Populations in Health and Disease

  1. 352 pages
  2. English
  3. PDF
  4. Available on iOS & Android
eBook - PDF

The Genetics of African Populations in Health and Disease

About this book

The birthplace of modern humans, Africa, has the highest genetic diversity in the world, yet it remains vastly understudied. With biomedical research increasingly focused on human variation, studying the large population size and number of mutations in African genomes could unravel the complexity of phenotypic traits underlying the biology of our species and hold huge potential for scientific and medical advances. An initial chapter 'conceptualizes Africa', providing relevant terminology. The first section covers genetic history and population structure. The next section looks at the genetic basis of common infectious diseases, such as leishmaniasis, malaria and tuberculosis, with a final part considering common non-communicable diseases, such as diabetes, hypertension, obesity, heart disease and cancer. Gene environment interaction under globalization and the burden of diseases of lifestyle are included. For researchers and graduate students in biological anthropology, genetic anthropology, human and population genetics, and public health.

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Information

Publisher
Cambridge University Press
Year
2019
Print ISBN
9781107072022
eBook ISBN
9781108695077
Topic
Biological Sciences
Subtopic
Zoology
Index
Biological Sciences

Table of contents

  1. Cover
  2. Half-title
  3. Series information
  4. Title page
  5. Copyright information
  6. Contents
  7. List of Contributors
  8. 1 Reflections on Conceptualizing Africa for Biological Studies with a Historical Component: A Small Essay
  9. 2 History and Genetics in Africa: Multidisciplinary Efforts
  10. 3 Disease, Selection, and Evolution in the African Landscape
  11. 4 Genetic Susceptibility to Visceral Leishmaniasis
  12. 5 Genetics of Infection in Sub-Saharan Africa: What Can the Study of Mendelian Immunodeficiency Disorders Contribute?
  13. 6 Pharmacogenomics and Infectious Diseases in Africa: An Evolutionary Perspective
  14. 7 A Glimpse into Pharmacogenomics in Africa
  15. 8 Genomics of Cardiometabolic Disorders in Sub-Saharan Africa
  16. 9 Breast Cancer in African Populations
  17. 10 Sociobiological Transition and Cancer: Prospects for Africa
  18. 11 The Genetic Epidemiology of Orphan Diseases in North Africa
  19. 12 Birth Defects and Genetic Disease in Sub-Saharan Africa
  20. 13 Neurogenetic Disorders in Africa: Hereditary Spastic Paraplegia: A Case Study
  21. 14 Enabling Genomic Revolution in Africa: History and Impact of the African Society of Human Genetics and the Human Heredity and Health in Africa Initiative
  22. Index

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Yes, you can access The Genetics of African Populations in Health and Disease by Muntaser E. Ibrahim,Charles N. Rotimi in PDF and/or ePUB format, as well as other popular books in Biological Sciences & Zoology. We have over 1.5 million books available in our catalogue for you to explore.