Microbiome Metabolome Brain Vagus Nerve Circuit in Disease and Recovery

Elena L. Paley

• Publisher: Academic Press
• Year: 2023
• Print ISBN: 9780443191220
• eBook ISBN: 9780443151989
• Topic: Medicine
• Subtopic: Neurology

Microbiome Metabolome Brain Vagus Nerve Circuit in Disease and Recovery focuses on the emerging hypothesis of a dysfunctional microbiome metabolome vagus nerve brain circuit in Alzheimer's disease and associated diseases and medical conditions, including dementia, aging, COVID-19, autoimmune conditions, and inflammatory skin condition rosacea, which may increase the risk of other conditions. This book also discusses the vagus nerve-related conditions, including Arnold's reflex, laryngopharyngeal reflux, duodenogastric reflux, gastroesophageal reflux, and related pulmonary diseases. The subjects covered in the book also address an important question of which one is more important for human health and intellectual abilities: the human genome or the human microbiome? The conceptual model of food and gut microbial tryptamine vagus nerve circuit is also presented in this book. - Addresses the emerging hypothesis of a dysfunctional microbiome vagus nerve brain circuit in Alzheimer's disease and associated diseases and medical conditions - Covers dementia, aging, COVID-19, autoimmune conditions, and inflammatory skin condition rosacea - Presents the conceptual model of food and gut microbial tryptamine vagus nerve circuit - Covers human health and intellectual abilities in the context of both the human genome and the human microbiome

Table of contents

• Title of Book
• Cover image
• Title page
• Table of Contents
• Copyright
• Chapter 1 Introduction: Microbial metabolite interference of protein biosynthesis in neurodegenerative, neurodevelopmental, and other disorders; microbial metabolites hijacking vagus nerve
• Chapter 2 COVID-19: Scientific progress
• Chapter 3 Viral-bacterial interactions in diseases
• Chapter 4 Vagus nerve: Acid reflux, parietal cells, carpal tunnel syndrome, Alzheimer’s disease, COVID-19, stroke, cancer, and other diseases
• Chapter 5 Vagus nerve circuit: Microbiome—tryptophan metabolites—receptors and synapses
• Chapter 6 Glutamate and glutamate receptors in vagus nerve pathways and in Alzheimer’s disease
• Chapter 7 Aminoacyl tRNA synthetase multiple forms in autoimmune and infectious diseases
• Chapter 8 Crystalized aromatic L-amino acid decarboxylase from bacteria Micrococcus percitreus catalyzing decarboxylation of tryptophan and L-DOPA (Levodopa or 3,4-dihydroxy-L-phenylalanine)
• Chapter 9 Health effects of elevated CO2 levels, sparkling mineral water, seltzer carbonated water
• Chapter 10 Microbial antigens, allergies, and antibodies to microbial allergens: Significance of preexisting antibodies and stress for vaccination
• Chapter 11 Smell and taste identification deficits in disease
• Chapter 12 Microorganisms producing biogenic amines: From food to human body
• Chapter 13 Human genome or human microbiome genes: Which one is more important for human health and intellectual abilities?
• Chapter 14 Microorganisms used in agriculture, consumed from environment and associated with the edible raw fruits, vegetables, herbs, sprouts, and mushrooms
• Chapter 15 Molecular and cell aggregation: Biogenic amines, proteins, platelets, and microbial pathogens
• Chapter 16 Colonic diverticular disease as a risk factor for neurodegenerative and associated diseases
• Chapter 17 Alzheimer’s disease, dementia, aging, and COVID-19
• Chapter 18 Existing vaccines and new and old tools
• Chapter 19 Serotonin syndrome in neurodegenerative diseases and COVID-19: Mechanisms and consequences of intestinal infection
• Chapter 20 Circulating cell-free mitochondria and membrane vesicles
• Chapter 21 Protein synthesis inhibition in neuronal activities
• Chapter 22 Rosacea and associated medical disorders
• Chapter 23 Bacterial internalization in cancer and other medical conditions: Intracellular pathogens
• Chapter 24 Ocular changes resulting from reading and writing on smartphone and computer: Computer vision syndrome, dry eye disease, meibomian gland dysfunction, chalazion, occupational overuse syndrome
• Chapter 25 Viral infections in vagus nerve
• Chapter 26 Microbial tryptamine in Type 1, Type 2, and Type 3 diabetes
• Index