Angiotensin

From the Kidney to Coronavirus

Paul M. Pilowsky

• Publisher: Academic Press
• Year: 2023
• Print ISBN: 9780323996181
• eBook ISBN: 9780323996198
• Topic: Biological Sciences
• Subtopic: Cell Biology
• Index: Biological Sciences

Angiotensin: From the Kidney to Coronavirus, a new volume in the Molecular Mediators in Health and Disease series, presents the communication role of the hormone in both health and disease states. Beyond the most common conditions, the book also explores the role of Angiotensin in infectious diseases, like COVID-19. Sections provide background to its discovery and role in homeostasis, focus on molecular biology aspects, including genetics and measurements of its associated proteins, describe the specific actions of angiotensin in normal physiology with different organ systems, survey different classes of drugs that act on the Renin-angiotensin-aldosterone system, cover non-angiotensin II peptides, and more. The final part of the book is dedicated to angiotensin's role in disease states, making this the ideal reference for researchers in life sciences interested in understanding the physiological role of Angiotensin in a complete fashion. Research physicians will also benefit from the book's complete coverage of organ systems and diseases where Angiotensin plays a key role. - Covers the traditional disorders related to Angiotensin and new findings like its role in infectious diseases like COVID-19 - Offers an overview of all important aspects of angiotensin, from discovery to clinical application, from physical and chemical properties to the physiological/cellular interaction - Expands on the role of angiotensin beyond the individual system the researcher is focusing, providing a comprehensive coverage of the additional effects at cell, tissue, organ, and system levels

Table of contents

• Title of Book
• Cover image
• Title page
• Table of Contents
• Copyright
• List of contributors
• Preface
• Chapter 1 Regulation of sympathetic nerve activity by the central angiotensin system in heart failure
• Chapter 2 The contribution of angiotensin peptides to cardiovascular neuroregulation in health and disease
• Chapter 3 Renin–angiotensin system and inflammation
• Chapter 4 Targeting renin–angiotensin system: a strategy for drug development against neurological disorders
• Chapter 5 Pharmacology of angiotensin in renovascular diseases
• Chapter 6 The role of angiotensins in the pathophysiology of human pregnancy
• Chapter 7 Hematopoietic bone marrow renin-angiotensin system in health and disease
• Chapter 8 Angiotensin II as a mediator of renal fibrogenesis
• Chapter 9 Angiotensin and atherosclerotic vascular disease
• Chapter 10 ACE2 in pulmonary diseases
• Chapter 11 Renin–angiotensin–aldosterone system inhibitors. New and old approaches
• Chapter 12 Aspects of the intracellular renin–angiotensin system
• Chapter 13 Interactions between the renin–angiotensin–aldosterone system and COVID-19: pharmacological interventions
• Chapter 14 Angiotensin II and its action within the brain during hypertension
• Chapter 15 Morphological aspect of the angiotensin-converting enzyme 2
• Chapter 16 The renin-angiotensin system in the eye: implications on health and disease
• Chapter 17 Brain renin–angiotensin system in the injured brain: the role of astrocytes and microglia
• Chapter 18 Angiotensin and COVID-19
• Chapter 19 Transgenic animal models for the functional analysis of ACE2
• Chapter 20 Role of angiotensin in different malignancies
• Chapter 21 ACE2/angiotensin-(1–7)/mas receptor axis in the central nervous system: physiology and pathophysiology
• Chapter 22 The therapeutic potential of angiotensin-(1–7)
• Chapter 23 Angiotensin and pain
• Chapter 24 The renin-angiotensin system, emotional stress and anxiety
• Chapter 25 Angiotensins in obesity: focus on white adipose tissue
• Chapter 26 Angiotensin in the gut: roles in inflammatory bowel disease
• Chapter 27 The renin–angiotensin system in gastrointestinal functions
• Chapter 28 Angiotensin in shock: experimental and clinical studies
• Chapter 29 Angiotensin II and astrocytes relevance in mental disorders
• Chapter 30 Angiotensin II and polycystic kidney disease
• Chapter 31 The role of angiotensin peptides in the brain during health and disease
• Index