Advances in Animal Experimentation and Modeling

Understanding Life Phenomena

Ranbir Chander Sobti

• Publisher: Academic Press
• Year: 2021
• Print ISBN: 9780323905831
• eBook ISBN: 9780323910446
• Topic: Biological Sciences
• Subtopic: Biology
• Index: Biological Sciences

Exploration in Laboratory Animal Sciences Understanding Life Phenomena updates our knowledge about the newer technologies such as molecular biology, genomics including sequencing, proteomics, transcriptomics, cell culture, stem cell culture, transgenesis and their translation to understand systematics and phylogeny of laboratory animals at molecular level. In seven sections Exploration in Laboratory Animal Sciences Understanding Life Phenomena resolves issues of conservation, applications in environment monitoring, production of drugs and others. Comparative research has enabled use of domestic animal models that translate the advances in basic biosciences to the schemes for human welfare including medicine. Molecular geneticists are unravelling the complexities of mammalian genes and the field of biotechnology is maturing at a fast pace. Additionally, research focused on immunology and animal behavior offer new insight into ways of enhancing animal welfare. The rise in consumption of animal proteins in addition to the challenges of sustaining our natural resources has given animal scientists a vast array of opportunities to engage in integrative systems-based research for meeting the challenges that behold us.Exploration in Laboratory Animal Sciences Understanding Life Phenomena also discusses the manipulation of animals as factories for the production of safe foods, drugs, and sensors and others to meet the contemporary challenges faced by mankind in the new world order created by pandemic of Covid 19. It also includes several chapters on the causation and management of certain diseases and impact of microbes on life.- Provides insight to newer and futuristic technologies to understand disease process and drug design by animal models- Addresses a wide variety of species and covers a wide variety of topics (such as animal species, the laboratory setting, regulatory guidelines, and ethical considerations) to fully prepare for work with all types of animals- Gives a perspective on laboratory animal use that allows to explain the benefits of animal use as required by veterinary technology program accreditation procedure- Includes examples of animal bio-technological techniques (including stem cell and tissue engineering) for their applications to humanity- Offers new insight into ways of enhancing animal welfare by the inclusion of research results focused on immunology and laboratory animal behavior

Table of contents

• Cover
• Title page
• Table of Contents
• Copyright
• Dedication
• Contents
• List of contributors
• Preface
• List of Illustrations
• List of Tables
• Chapter 1 : Emerging techniques in biological sciences
• Chapter 2 : Molecular basis of animal systematics including barcoding
• Chapter 3 : Mitochondrial DNA: a tool for elucidating molecular phylogenetics and population
• Chapter 4 : Somatic cell nuclear transfer in cellular medicine and biopharming
• Chapter 5 : Animal cloning: perspectives for futuristic medicine
• Chapter 6 : CRISPR/Cas9 system and prospects in animal modeling of neurodegenerative diseases
• Chapter 7 : Semen quality biomarkers for improvement of production in livestock
• Chapter 8 : Animal models and their substitutes in biomedical research
• Chapter 9 : Experimental models for investigating the pathogenesis of heart failure
• Chapter 10 : Animal models of inflammatory musculoskeletal diseases for tissue engineering and regenerative medicine: updates and translational application
• Chapter 11 : Selection of experimental models mimicking human pathophysiology for diabetic microvascular complications
• Chapter 12 : Exploration on different animal models used in drug-induced adverse reactions research; current scenario and further prospectives
• Chapter 13 : Animal models for hepatoxicity
• Chapter 14 : Drosophila embryo as experimental model: lessons learnt from genes in axis formation
• Chapter 15 : Exploration of biological science in extreme environment: an Indian experience at the Arctic
• Chapter 16 : Parlance of insect systematics: from classical to molecular—the journey has been long
• Chapter 17 : Parasites in a changing world
• Chapter 18 : Ambient ecological conditions of the Gangetic dolphin- Platanista gangetica gangetica of river Ganga, between Varanasi to Farakka
• Chapter 19 : Entomopathogenic nematode in national development through enhancing the socio-economic condition of Indian farmers
• Chapter 20 : Molecular studies of pest termites in India
• Chapter 21 : Roadmap for wildlife research and conservation in India
• Chapter 22 : Flying fox: threats and global conservation status
• Chapter 23 : Importance of need-based and applied research for conservation of animal fauna towards national development—an insight
• Chapter 24 : Strategies for characterizing and protecting animal resources for future generations
• Chapter 25 : Buffaloes for nutritional secure and economically empowered rural India
• Chapter 26 : Livestock sector: an integral component for country’s food and social security
• Chapter 27 : Proteomics-based advancements in research toward sustainable production from dairy livestock
• Chapter 28 : Artificial insemination: scope and challenges for indian dairy sector
• Chapter 29 : Livestock health: current status of helminth infections and their control for sustainable development
• Chapter 30 : Harnessing potential of A2 milk in India: an overview
• Chapter 31 : Understanding heat stress response in dairy animals: an overview
• Chapter 32 : Livestock sector between pushing and pulling factors-evolving scenario for national livestock development
• Chapter 33 : Parasite diversity strategies under influence of pollutants
• Chapter 34 : Parasites : futuristic indicators of an altered aquatic environment
• Chapter 35 : Effect of climate change on mosquito population and changing pattern of some diseases transmitted by them
• Chapter 36 : New dimensions in self employment for sustainability in a changing environment
• Index
• A