Essentials of Pharmatoxicology in Drug Research, Volume 1
eBook - ePub

Essentials of Pharmatoxicology in Drug Research, Volume 1

Toxicity and Toxicodynamics

  1. 752 pages
  2. English
  3. ePUB (mobile friendly)
  4. Available on iOS & Android
eBook - ePub

Essentials of Pharmatoxicology in Drug Research, Volume 1

Toxicity and Toxicodynamics

About this book

Toxicity and Toxicodynamics, Volume One in the Essentials of Pharmatoxicology in Drug Research series provides an overview on the essentials of toxicology, risk assessment and the mechanisms. Topics discussed include the types of cellular responses to chemical toxicants, mechanisms of drug toxicity, and their relevance to pharmaceutical product development. The book examines omics and computer-aided technologies for mechanistic and predictive toxicology and covers state-of-art testing in the evaluation of detrimental pathways, dose selection in toxicity studies, as well as the role of regulatory agencies in toxicity studies.In addition, there is also discussion on clinical interventions such as pharmacotherapy and managed care strategies for acute poisoning. This volume is a valuable resource to those learning more about the drug development process related to toxicology and those who want to get an update on newer concepts on the toxicology aspect of drug research.- Examines toxicological risk assessment in drug research- Discusses toxicity mechanisms- Covers risk assessment and the use of omics and computational technologies in mechanistic and predictive toxicology- Offers clinical interventions and managed care as a result of toxic injury and acute poisoning

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Yes, you can access Essentials of Pharmatoxicology in Drug Research, Volume 1 by Rakesh Kumar Tekade in PDF and/or ePUB format, as well as other popular books in Medicine & Medical Theory, Practice & Reference. We have over one million books available in our catalogue for you to explore.

Table of contents

  1. Cover
  2. Front Matter
  3. Table of Contents
  4. Copyright
  5. Dedication
  6. List of contributors
  7. List of Illustrations
  8. List of Tables
  9. Chapter 1 : Understanding pharmacotoxicology
  10. Chapter 2 : Toxicology in drug research
  11. Chapter 3 : Role of microRNAs in toxicology
  12. Chapter 4 : Exosomes as mediators of chemical-induced toxicity
  13. Chapter 5 : Drug-induced oxidative stress as a mechanism of toxicity
  14. Chapter 6 : Role of “toxicant-induced loss of tolerance” in the emergence of disease
  15. Chapter 7 : Types of cellular responses to chemical toxicants
  16. Chapter 8 : Toxicant-induced injury and tissue repair
  17. Chapter 9 : Computer-aided technologies in drug discovery and toxicity prediction
  18. Chapter 10 : Predicting toxicity from chemical structure of a drug compound
  19. Chapter 11 : Toxicokinetics and organ-specific toxicity
  20. Chapter 12 : Drug-induced nephrotoxicity and its biomarkers
  21. Chapter 13 : Mechanism of drug-induced neurotoxicity and its management
  22. Chapter 14 : Thermal processing and food-related toxicants
  23. Chapter 15 : Medication errors and approaches for its prevention
  24. Chapter 16 : Understanding the bioaccumulation of pharmaceuticals and personal care products
  25. Chapter 17 : Toxicity of dental materials and ways to screen their biosafety
  26. Chapter 18 : Clinical detoxification of the body from chemical toxicants
  27. Chapter 19 : Molecular mechanisms of the chemopreventive role of dietary phytochemicals
  28. Chapter 20 : Toxicity labels
  29. Chapter 21 : Toxic potential indicator
  30. Chapter 22 : Concept of pharmacotherapy and managed care in clinical interventions
  31. Chapter 23 : Understanding the connection between dietary supplementation and inadvertent doping
  32. Chapter 24 : Cells and tissue-based models as a rational substitute in toxicity testing
  33. Chapter 25 : Regulatory agencies for toxicological studies
  34. Chapter 26 : Key challenges for toxicologists in the 21st century
  35. Index
  36. A