Stereochemistry and Organic Reactions

Conformation, Configuration, Stereoelectronic Effects and Asymmetric Synthesis

Dipak Kumar Mandal

• Publisher: Academic Press
• Year: 2021
• Print ISBN: 9780128240922
• eBook ISBN: 9780128240939
• Topic: Physical Sciences
• Subtopic: Organic Chemistry

Stereochemistry and Organic Reactions: Conformation, Configuration, Stereoelectronic Effects and Asymmetric Synthesis provides coverage on the stereochemistry of reactions of all mechanistic types, ranging from ionic, pericyclic and transition metal-catalyzed to radical and photochemical. Chapters cover acyclic molecules, cyclic molecules, the stereochemistry of organic reactions, the perturbation molecular orbital theory for the origin of stereoelectronic effects, and an introduction to the principles of stereoselectivity and hierarchical levels of asymmetric synthesis. Each chapter includes problems that reinforce main themes, making it valuable to students, teachers and researchers working in organic, biological and medicinal chemistry, as well as biologists, pharmacologists, polymer chemists and chemists. - Presents a holistic and unified approach to stereochemical understanding and predictions, covering reactions of all mechanistic classes - Includes two background chapters on perturbation theory and stereoselective principles, along with asymmetric designs - Features novel rules and mnemonics to delineate product stereochemistry - Includes up-to-date coverage with over 1300 selective references

Table of contents

• Stereochemistry and Organic Reactions
• Introduction
• Chapter 1 Acyclic molecules 1: Conformation and symmetry
• Chapter 2 Acyclic molecules 2: Configuration and resolution
• Chapter 3 Cyclic molecules: Configuration and conformation
• Introduction
• Chapter 4 Perturbation theory and organic reactions
• Chapter 5 Introduction to stereospecificity, stereoselectivity and asymmetric synthesis
• Introduction
• Chapter 6 Ionic reactions 1: Fundamental stereochemistry
• Chapter 7 Ionic reactions 2: Diastereoselectivity and asymmetric synthesis
• Chapter 8 Pericyclic reactions 1: Basic stereochemistry
• Chapter 9 Pericyclic reactions 2: Asymmetric synthesis
• Chapter 10 Transition metal-catalysed reactions: Diastereoselectivity and asymmetric synthesis
• Chapter 11 Radical reactions: Stereochemistry and asymmetric synthesis
• Chapter 12 Photochemical reactions: Stereochemistry and asymmetric synthesis
• Appendix Answers to problems
• Index