Autophagy and Metabolism

Potential Target for Cancer Therapy

Dhruv Kumar, Shailendra Asthana

• Publisher: Academic Press
• Year: 2022
• Print ISBN:
  9780323998796
• eBook ISBN:
  9780323999458
• Topic: Biological Sciences
• Subtopic: Biology
• Index: Biological Sciences

Autophagy and Metabolism: Potential Target for Cancer Therapy presents updates on autophagy in cancer metabolism and how it can be used to develop new, more efficient treatments. Written by experts in the field, the book presents recent research and explains how to translate it to the clinical setting. Sections discuss tumor cell metabolism and autophagy as therapeutic targets, autophagy regulation in cancer, signaling pathways in metabolic dysregulation in solid tumors, metabolic stress and cell death pathways, and the role of the tumor microenvironment. In addition, topics cover combined targeting autophagy, metabolism for cancer therapy, and the autophagy effect on immune cell metabolism. This will be a valuable resource for researchers, oncologists, graduate students, and members of the biomedical field who are interested in learning more about the interaction between autophagy and cancer metabolism. - Presents valuable and updated information on the mechanisms of autophagy in cancer metabolism - Discusses the various metabolic pathways linked with autophagy that can be a major target for chemotherapeutic strategies - Explains how autophagy supports tumor growth by activating metabolic phenotypes in cancer cells and the therapeutic interventions available to halt the process

Table of contents

• Title of Book
• Cover image
• Title page
• Table of Contents
• Copyright
• List of contributors
• Preface
• Chapter 1 Metabolic dysregulation in cancer progression
• Chapter 2 Molecular dynamics of autophagy in cancer metabolism
• Chapter 3 Tumor cell metabolism and autophagy as therapeutic targets
• Chapter 4 Autophagy regulation in cancer: current knowledge on action and therapy
• Chapter 5 Signaling pathways in metabolic dysregulation in solid tumors
• Chapter 6 Autophagy in arsenic exposed population and cancer patients
• Chapter 7 Autophagy in cancer-associated fibroblasts: biology and targeting
• Chapter 8 Autophagy and metabolic regulation in cancer and its application in drug discovery
• Chapter 9 Mitophagy in cancer and cancer stem cells: a role in metabolic reprogramming
• Chapter 10 Combined targeting autophagy and metabolism for cancer therapy
• Chapter 11 Designing metabolic target-specific inhibitors for cancer therapy
• Chapter 12 Interplay between gut microbiota and autophagy in human health
• Chapter 13 Autophagy in infection-mediated cancers
• Index