Bone Cancer
eBook - ePub

Bone Cancer

Bone Sarcomas and Bone Metastases - From Bench to Bedside

  1. 1,078 pages
  2. English
  3. ePUB (mobile friendly)
  4. Available on iOS & Android
eBook - ePub

Bone Cancer

Bone Sarcomas and Bone Metastases - From Bench to Bedside

About this book

Bone Cancer: Bone Sarcomas and Bone Metastases - From Bench to Bedside, Third Edition comprehensively investigates key discoveries in the field of bone biology. New aspects of bone cancer biology are treated in new chapters covering exosomes, autophagy, and metabolism. These have led to the development of entirely new areas for investigation, such as therapies which combine surgery and biological approaches. The Third Edition expands on the original overview of bone cancer development (physiology and pathophysiology), with 40% new material. Each chapter has been written by internationally recognized specialists on the bone cancer microenvironment, bone metastases, osteoclast biology in bone cancer, proteomics, bone niche, circulating tumor cells, and clinical trials. Given the global prevalence of breast and prostate cancers, knowledge of bone biology has become essential for everyone within the medical and cancer research communities. Bone Cancer: Bone Sarcomas and Bone Metastases - From Bench to Bedside continues to offer the only translational reference to cover all aspects of primary bone cancer and bone metastases. This revision opens the door to myeloma with two short chapters dedicated to this bone-associated disease. - Covers the broad field of bone sarcomas and bone metastases from basic research to clinical approaches - Presents comprehensive and translational overview of biological and clinical aspects of bone cancers, discussing pathophysiology from genetic and molecular levels using the most recent evidence - Provides a common language for cancer researchers, bone biologists, oncologists, and radiologists to discuss bone tumors and how bone cancer metastases affects each major organ system - Offers insights to research clinicians (oncologists and radiologists) into understanding the molecular basis of bone cancer, leading to more well-informed diagnoses and treatment of tumors and metastases - Offers insights to bone biologists into how clinical observations and practices can feed back into the research cycle and, therefore, can contribute to the development of more targeted genomic and proteomic assays

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Yes, you can access Bone Cancer by Dominique Heymann in PDF and/or ePUB format, as well as other popular books in Biological Sciences & Endocrinology & Metabolism. We have over one million books available in our catalogue for you to explore.

Table of contents

  1. Bone Cancer
  2. Chapter 1 Cancer
  3. Chapter 2 Epidemiology of primary bone tumors and economical aspects of bone metastases
  4. Chapter 3 Mammalian models of bone sarcomas
  5. Chapter 4 In vivo models used in studies of bone metastases
  6. Chapter 5 Zebrafish models for studying bone tumors
  7. Chapter 6 Use of machine learning in bone cancers
  8. Chapter 7 Artificial intelligence for bone cancer imaging
  9. Chapter 8 Technical aspects
  10. Chapter 9 Bone niche and bone metastases
  11. Chapter 10 Bone, a fertile soil for tumor development
  12. Chapter 11 Osteomimicry
  13. Chapter 12 The role of mesenchymal stem cells in bone cancer
  14. Chapter 13 Technical approaches for studying the communications between osteocytes and cancer cells
  15. Chapter 14 Osteocytes and bone tumor niche
  16. Chapter 15 Immune functions of osteoclasts
  17. Chapter 16 The immune environment of bone sarcomas
  18. Chapter 17 Macrophages and pathophysiology of bone cancers
  19. Chapter 18 Growth factors, cytokines, and pediatric malignant primary bones tumors
  20. Chapter 19 Effects of NF-κB manipulation on cancer-associated bone disease
  21. Chapter 20 Transforming growth factor-β and its signaling pathway in skeletal complications of malignancy
  22. Chapter 21 Extracellular vesicles, tumor growth, and the metastatic process
  23. Chapter 22 Connexin43 and development of primary bone tumors
  24. Chapter 23 Role of classical cannabinoid receptors in cancer-associated bone disease
  25. Chapter 24 Impact of the acid microenvironment on bone cancers
  26. Chapter 25 Hypoxia-inducible factor (HIF)–mediated effects of the hypoxic niche in bone cancer
  27. Chapter 26 Energy metabolism in bone tumors
  28. Chapter 27 EMT process in bone metastasis
  29. Chapter 28 Cancer stem cells and clonal evolution in bone sarcomas
  30. Chapter 29 Dormancy in cancer bone metastasis
  31. Chapter 30 Bone remodeling markers and bone cancer
  32. Chapter 31 Epigenetic heterogeneity in primary bone cancers
  33. Chapter 32 MicroRNA implication in therapeutic resistance and metastatic dissemination of bone-associated tumors
  34. Chapter 33 MicroRNAs and bone metastasis
  35. Chapter 34 Long noncoding RNA and bone sarcoma
  36. Chapter 35 Liquid biopsy in bone sarcomas and identification of new biomarkers
  37. Chapter 36 Disseminated tumor cells in bone marrow of cancer patients
  38. Chapter 37 Cytogenetics of bone tumors
  39. Chapter 38 Genetic aspects of primary bone tumors
  40. Chapter 39 Markers for bone sarcomas
  41. Chapter 40 Molecular pathology of osteosarcoma
  42. Chapter 41 Genomic and proteomic profiling of osteosarcoma
  43. Chapter 42 Ewing's sarcoma family of tumors
  44. Chapter 43 Molecular aspects of Ewing's sarcomas
  45. Chapter 44 Osteoclast-rich lesions of bone
  46. Chapter 45 Biology of cartilage tumor family
  47. Chapter 46 Imaging of bone sarcomas
  48. Chapter 47 Current therapeutic approaches of bone sarcomas
  49. Chapter 48 What is an adequate margin after bone tumor resection?
  50. Chapter 49 Regulated cell death and drug resistance in malignant bone tumors
  51. Chapter 50 Chondrosarcoma of bone
  52. Chapter 51 Radiation therapy for primary bone tumors
  53. Chapter 52 New therapeutic advances of bone sarcomas
  54. Chapter 53 The histopathology of skeletal metastases
  55. Chapter 54 Identification of new therapeutic targets of bone cancers by proteomic strategies
  56. Chapter 55 Interventional radiologic techniques in the management of bone tumors
  57. Chapter 56 Diagnosis of bone metastases in urological malignancies—an update
  58. Chapter 57 Mechanisms and management of bone cancer pain
  59. Chapter 58 Involvement of sympathetic nerves in bone metastasis
  60. Chapter 59 Pain control with palliative radiotherapy in patients with bone metastases
  61. Chapter 60 Palliative care for patients with bone metastases
  62. Chapter 61 Role of radiation therapy in patients with bone metastasis
  63. Chapter 62 Cellular and molecular actions of bisphosphonates
  64. Chapter 63 Bone-targeted agents and skeletal-related events in breast cancer patients with bone metastases
  65. Chapter 64 Bone metastases—current status of bone-targeted treatments
  66. Chapter 65 Therapies of bone metastases in castration-resistant prostate cancer
  67. Chapter 66 Targeted radionuclide therapy in bone cancer
  68. Chapter 67 The effects of anticancer therapies on bone metastases in breast cancer
  69. Chapter 68 Biological relationship between bone and myeloma cells
  70. Chapter 69 Recent therapeutic approaches in myeloma
  71. Index