TRP-Mediated Signaling
eBook - ePub

TRP-Mediated Signaling

  1. 248 pages
  2. English
  3. ePUB (mobile friendly)
  4. Available on iOS & Android
eBook - ePub

TRP-Mediated Signaling

About this book

The field of transient receptor potential (TRP) channels has gained momentum in recent years not only because of the 2021 Nobel Prize in Physiology or Medicine awarded to David Julius and Ardem Patapoutian for their discoveries of receptors for temperature and touch, but also because of the growing appreciation of the diverse and important physiological and pathophysiological functions of this diverse family of cation channels. In the past decade, there have been important discoveries in the TRP field: resolution of the 3-D structures of major subfamilies using single-particle cryogenic electron microscopy and X-ray crystallography, identification and development of selective agonists and antagonists for most TRP subfamily members, discovery of new human diseases associated with TRP gene mutations, as well as improved understanding of TRP channel function and regulation in various systems. These new discoveries are addressed in TRP-Mediated Signaling, a volume in the Methods in Signal Transduction book series.

Key Features

• Summarizes recent advances in the study of TRP channels

• Written by a team of leading international researchers

• Reviews physiological and pathophysiological functions of TRP channels

• Identifies diseases associated with TRP gene mutations

• Examines the evolution of temperature-sensing TRP channels

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Yes, you can access TRP-Mediated Signaling by Michael Xi Zhu in PDF and/or ePUB format, as well as other popular books in Biological Sciences & Biology. We have over one million books available in our catalogue for you to explore.

Information

Publisher
CRC Press
Year
2024
Print ISBN
9781032515335
eBook ISBN
9781040255919
Edition
1
Topic
Biological Sciences
Subtopic
Biology
Index
Biological Sciences

Table of contents

  1. Cover Page
  2. Half-Title Page
  3. Series Page
  4. Title Page
  5. Copyright Page
  6. Contents
  7. Preface
  8. About the Editor
  9. List of Contributors
  10. Series Preface
  11. Chapter 1 Recent Advances in the Structural Pharmacology of TRPC Channels
  12. Chapter 2 Characterizing the Structures and Regulation of TRPV Channels Using Cryo-EM
  13. Chapter 3 Role of the TRPM2 Channel as an ROS Sensing and Signaling Mechanism in Ischemia-Reperfusion Brain Damage
  14. Chapter 4 Investigating TRP Channel Function with Tools for High-Precision Manipulation of Gating Mechanism by Light
  15. Chapter 5 Pathophysiological Role of TRPC1 in Cell Function
  16. Chapter 6 TRPM4 and TRPM5 Channels as Chemical-to-Electrical Signal Converter
  17. Chapter 7 Physiological and Pathological Functions of TRPML1
  18. Chapter 8 TRP Channels in Cardiac Diseases
  19. Chapter 9 Vascular Function Mediators: TRP Channels in Endothelial and Smooth Muscle Cells
  20. Chapter 10 Study of TRP Channels in Stroke
  21. Chapter 11 Evolution of Thermosensitive TRP Channels as a Source of Sensory Diversification and Environmental Adaptation
  22. Index