Lahita's Systemic Lupus Erythematosus
eBook - ePub

Lahita's Systemic Lupus Erythematosus

  1. 730 pages
  2. English
  3. ePUB (mobile friendly)
  4. Available on iOS & Android
eBook - ePub

Lahita's Systemic Lupus Erythematosus

About this book

Systemic lupus erythematosus (SLE), commonly called lupus, is a chronic autoimmune disorder that can affect virtually any organ of the body. In lupus, the body's immune system, which normally functions to protect against foreign invaders, becomes hyperactive, forming antibodies that attack normal tissues and organs, including the skin, joints, kidneys, brain, heart, lungs, and blood. Lupus is characterized by periods of illness, called flares, and periods of wellness or remission. Because its symptoms come and go and mimic those of other diseases, lupus is difficult to diagnose. There is no single laboratory test that can definitively prove that a person has the complex illness.To date, lupus has no known cause or cure. Early detection and treatment are the key to a better health outcome and can usually lessen the progression and severity of the disease. Anti-inflammatory drugs, antimalarials, and steroids (such as cortisone and others) are often used to treat lupus. Cytotoxic chemotherapies, like those used in the treatment of cancer, are also used to suppress the immune system in lupus patients. A new edition of this established and well-regarded reference combines basic science with clinical science to provide a translational medicine model. Systemic Lupus Erythematosus, Sixth Edition, is a useful reference for specialists in the diagnosis and management of patients with SLE, a tool for measurement of clinical activity for pharmaceutical development and basic research of the disease, and a reference work for hospital libraries. - Completely updated, revised, and expanded with the most comprehensive and accessible reference on SLE for clinicians and scientists - Full-color presentation throughout the book - Provides the latest information available on diagnosis and treatment - Incorporates an international panel of authors who are experts in their fields, with an emphasis on young, cutting-edge scientists and physicians

Frequently asked questions

Yes, you can cancel anytime from the Subscription tab in your account settings on the Perlego website. Your subscription will stay active until the end of your current billing period. Learn how to cancel your subscription.
At the moment all of our mobile-responsive ePub books are available to download via the app. Most of our PDFs are also available to download and we're working on making the final remaining ones downloadable now. Learn more here.
Perlego offers two plans: Essential and Complete
  • Essential is ideal for learners and professionals who enjoy exploring a wide range of subjects. Access the Essential Library with 800,000+ trusted titles and best-sellers across business, personal growth, and the humanities. Includes unlimited reading time and Standard Read Aloud voice.
  • Complete: Perfect for advanced learners and researchers needing full, unrestricted access. Unlock 1.4M+ books across hundreds of subjects, including academic and specialized titles. The Complete Plan also includes advanced features like Premium Read Aloud and Research Assistant.
Both plans are available with monthly, semester, or annual billing cycles.
We are an online textbook subscription service, where you can get access to an entire online library for less than the price of a single book per month. With over 1 million books across 1000+ topics, we’ve got you covered! Learn more here.
Look out for the read-aloud symbol on your next book to see if you can listen to it. The read-aloud tool reads text aloud for you, highlighting the text as it is being read. You can pause it, speed it up and slow it down. Learn more here.
Yes! You can use the Perlego app on both iOS or Android devices to read anytime, anywhere — even offline. Perfect for commutes or when you’re on the go.
Please note we cannot support devices running on iOS 13 and Android 7 or earlier. Learn more about using the app.
Yes, you can access Lahita's Systemic Lupus Erythematosus by Robert G. Lahita in PDF and/or ePUB format, as well as other popular books in Medicine & Immunology. We have over one million books available in our catalogue for you to explore.

Information

Publisher
Academic Press
Year
2021
eBook ISBN
9780323914888
Edition
6
Topic
Medicine
Subtopic
Immunology

Table of contents

  1. Cover
  2. Front Matter
  3. Table of Contents
  4. Copyright
  5. Dedication
  6. Contributors
  7. Foreword
  8. Foreword from the First Edition
  9. Preface to Edition 6, Systemic Lupus Erythematosus
  10. Acknowledgment
  11. History of lupus erythematosus
  12. List of Illustrations
  13. List of Tables
  14. Chapter 1 : Major histocompatibility complex and SLE
  15. Chapter 2 : Lupus susceptibility genes
  16. Chapter 3 : Epigenetics in systemic lupus erythematosus and the integration of molecular pathways
  17. Chapter 4 : Autoantigens, antigenic mimicry, and immune complexes
  18. Chapter 5 : B-cell biology, tolerance, and autoantibodies
  19. Chapter 6 : T-cell biology, tolerance, and regulation
  20. Chapter 7 : Polymorphonuclear cells
  21. Chapter 8 : Metabolic and mitochondrial dysfunction in SLE
  22. Chapter 9 : Immunopathogenesis: the role of mucosal and skin microbiota in SLE
  23. Chapter 10 : Complement and SLE
  24. Chapter 11 : Interferons and cytokines in SLE pathogenesis and therapy
  25. Chapter 12 : Innate immunity in SLE pathogenesis
  26. Chapter 13 : Sex bias in SLE
  27. Chapter 14 : Mechanisms of tissue injury in lupus nephritis
  28. Chapter 15 : The skin
  29. Chapter 16 : The brain in SLE: mechanisms and detection of injury and therapeutic strategies
  30. Chapter 17 : The role of infections in SLE pathogenesis
  31. Chapter 18 : Tissue injury—the biology: SLE-associated vascular disease and antiphospholipid syndrome
  32. Chapter 19 : Epidemiology of SLE and related diseases: incidence, prevalence, and mortality
  33. Chapter 20 : The clinical presentation of systemic lupus erythematosus and laboratory diagnosis
  34. Chapter 21 : Passively acquired lupus in the fetus and neonate
  35. Chapter 22 : Systemic lupus erythematosus in children
  36. Chapter 23 : Environmental and drug-induced lupus
  37. Chapter 24 : Reproductive health
  38. Chapter 25 : Monitoring disease activity
  39. Chapter 26 : Overlap syndromes
  40. Chapter 27 : Nervous system
  41. Chapter 28 : Skin
  42. Chapter 29 : Kidney disease
  43. Chapter 30 : Cardiovascular disease in lupus
  44. Chapter 31 : Pulmonary manifestations of systemic lupus erythematosus
  45. Chapter 32 : GI hepatic and nonhepatic diseases
  46. Chapter 33 : Musculoskeletal system: articular disease, myositis, and bone metabolism
  47. Chapter 34 : Clinical presentation of antiphospholipid syndrome
  48. Chapter 35 : Hematology: cytopenias
  49. Chapter 36 : Malignancy risk and screening
  50. Chapter 37 : Antimalarial drugs (and lupus)
  51. Chapter 38 : Glucocorticoids
  52. Chapter 39 : Immunosuppressive therapy in SLE
  53. Chapter 40 : Pipeline therapies and future drug development
  54. Chapter 41 : Challenges of systemic lupus clinical trials
  55. Index
  56. A