Receptor Tyrosine Kinases in Neurodegenerative and Psychiatric Disorders
eBook - ePub

Receptor Tyrosine Kinases in Neurodegenerative and Psychiatric Disorders

  1. 604 pages
  2. English
  3. ePUB (mobile friendly)
  4. Available on iOS & Android
eBook - ePub

Receptor Tyrosine Kinases in Neurodegenerative and Psychiatric Disorders

About this book

Overexpression of receptor tyrosine kinases (RTKs) has been implicated in cancer. Increasing evidence suggests that dysregulation of RTKs is reported in many neurodegenerative and psychiatric disorders. Receptor Tyrosine Kinases in Neurodegenerative and Psychiatric DisordersĀ provides a fundamental, pragmatic map of RTKs structure, activation, functions, mechanism of action, gene regulation, and signaling pathways in developing central nervous system (CNS), adult normal CNS, neurodegenerative and psychiatric disorders. Additionally, the structure, function, activation, and therapeutic potential of many growth factors have been covered. Here, international experts in the field offer a comprehensive discussion of results of pre-clinical and clinical studies of repositioning of anti-cancer receptor tyrosine kinase inhibitorsĀ (RTKIs) and other promising protein kinase inhibitors in various neurodegenerative disorders including, Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, Huntington's disease, and multiple sclerosis, and psychiatric disorders including, anxiety, depression, alcohol use disorder, and schizophrenia. In addition, the book discusses the obstacles and opportunities for the potential repositioning of kinase inhibitors in neurodegenerative and psychiatric disorders. - Provides a thorough overview of RTKs biology and their role in health and disease progression and modulation - Highlights RTK families and the numerous receptors within each subfamily - Examines RTKIs and other protein kinase inhibitors in pre-clinical and clinical trials in both neurodegenerative and psychiatric disorders - Gives future directions of possible safe effective targeted RTKIs and other protein kinase inhibitors that may be repositioned in various neurodegenerative and psychiatric disorders - Includes chapter contributions from renowned experts in biology, pharmacology, neurology, psychiatry, and oncology

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Yes, you can access Receptor Tyrosine Kinases in Neurodegenerative and Psychiatric Disorders by Heba Mohamed Mansour,Mahmoud Mohamed Khattab,Aiman Saad El-Khatib in PDF and/or ePUB format, as well as other popular books in Biological Sciences & Science Research & Methodology. We have over one million books available in our catalogue for you to explore.

Table of contents

  1. Title of Book
  2. Cover image
  3. Title page
  4. Table of Contents
  5. Copyright
  6. Dedication
  7. List of contributors
  8. Preface
  9. Acknowledgments
  10. Section I: Receptor tyrosine kinase in the central nervous system in health and disease
  11. Section II: Role of receptors tyrosine kinases (RTKs) in neurodegenerative and psychiatric disorders
  12. Section III: Therapeutic potential of RTK modulators in neurodegenerative and psychiatric disorders
  13. Index