
Schering Workshop on Pharmacokinetics, Berlin, May 8 and 9, 1969
Advances in the Biosciences
- 296 pages
- English
- PDF
- Available on iOS & Android
Schering Workshop on Pharmacokinetics, Berlin, May 8 and 9, 1969
Advances in the Biosciences
About this book
Advances in the Biosciences 5: Schering Workshop on Pharmacokinetics, Berlin, May 8 and 9, 1969 is a collection of papers presented at the Schering Workshop on Pharmacokinetics held in Berlin, Germany, on May 8 and 9, 1969. Contributors focus on advances in the field of pharmacokinetics, including the use of digital computers in defining pharmacokinetic parameters and of mathematical models in the study of steroid dynamics. The pharmacokinetics of acetazolamide and endogenous substances is also described. This book is comprised of 19 chapters and begins with an overview of the basic concepts and experimental methods of pharmacokinetics, followed by a discussion on the general physico-chemical aspects of drug distribution. Subsequent chapters explore multiple dose elimination kinetics and drug accumulation in patients with normal and impaired kidney function; the application of analog and digital computers in pharmacokinetics; use of mathematical tools in defining pharmacokinetic parameters; and measurement of enteric absorption rate using a double tracer technique. Mathematical and statistical problems in pharmacokinetics are also presented. This monograph will be a useful resource for pharmacologists and biologists.
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Table of contents
- Front Cover
- Advances in the Biosciences 5
- Copyright Page
- Table of Contents
- Chapter 1.Introduction
- Chapter 2. Opening
- Chapter 3. Basic Concepts and Experimental Methods of Pharmacokinetics
- Chapter 4. General Physico-Chemical Aspects of DrugDistribution
- Chapter 5. Multiple Dose Elimination Kinetics and Drug Accumulation in Patients with Normal and with Impaired Kidney Function
- Chapter 6. The Application of the Analog Computer inPharmacokinetics
- Chapter 7. Use of Digital Computers in Defining PharmacokineticParameters
- Chapter 8. Use of Mathematical Tools in DefiningPharmacokinetic Parameters
- Chapter 9. Mathematical and Statistical Problems in Pharmacokinetics
- Chapter 10. The Formulation of Models to explain Blood andTissue Data on Distribution of Drugs and Tracers(With special Reference to Multi-CompartmentModels)
- Chapter 11. An Explicit Function for Rate Constant ofEntrance Concerning a Two-Compartment-Model
- Chapter 12. Mathematical Models in the Study of SteroidDynamics
- Chapter 13. The Measurement of Enteric Absorption Rateusing a Double Tracer Technique
- Chapter 14. Pharmacokinetics of Endogenous Substances
- Chapter 15. The Pharmacokinetics of Acetazolamide in Relation to its Use in the Treatment of Glaucomaand to its Effects as an Inhibitor of CarbonicAnhydrases
- Chapter 16. Pharmacokinetics in Clinical Drug Research
- Chapter 17. Pharmacokinetics of Human Drug Research
- Chapter 18. Panel Discussion
- Chapter 19. Closing Address