
Phosphorus Chemistry Directed Towards Biology
Lectures Presented at the International Symposium on Phosphorus Chemistry Directed Towards Biology, Burzenin, Poland 25-28 September 1979
- 240 pages
- English
- PDF
- Available on iOS & Android
Phosphorus Chemistry Directed Towards Biology
Lectures Presented at the International Symposium on Phosphorus Chemistry Directed Towards Biology, Burzenin, Poland 25-28 September 1979
About this book
Phosphorus Chemistry Directed Towards Biology presents an understanding of reaction mechanisms of organophosphorus compounds. This book discusses the development of analytical tools for the study of the chemistry of phosphorus, which promoted research in nucleic acid chemistry. Organized into 22 chapters, this book begins with an overview of the importance of the bacterial cell wall in maintaining the integrity of the cell in various environments. This text then examines the chemical problems concerning hypermodification and deprotection steps. Other chapters consider the reactive phosphorylating intermediates used in the oligonucleotide chemistry. This book discusses as well the possible role of phosphodiester triazolides and tetrazolides in the phosphotriester formation with arenesulfonyltriazolides and tetrazolides. The final chapter deals with the isolation of proteins involved in the synthesis and recognition of mRNA caps. This book is a valuable resource for phosphorus chemists, biologists, scientists, research workers, teachers, and students.
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Table of contents
- Front Cover
- Phosphorus Chemistry Directed Towards Biology
- Copyright Page
- Table of Contents
- FOREWORD
- CHAPTER 1. POLYMERS CONTAINING PHOSPHORUS IN BACTERIAL CELL WALLS
- CHAPTER 2. STUDIES ON OLIGORIBONUCLEOTIDES SYNTHESIS
- CHAPTER 3. REACTIVE PHOSPHORYLATING INTERMEDIATES IN THE NUCLEIC ACIDS CHEMISTRY
- CHAPTER 4. SYNTHESIS OF tRNAfMet FROM E. COLI
- CHAPTER 5.THE SYNTHESIS OF A POTENTIALLY METABOLICALLY-LABILE DERIVATIVE OF 2'-DEOXY-5-FLUOROURIDINE 5'-PHOSPHATE
- CHAPTER 6. SYNTHESIS AND BIOLOGICAL ACTIVITY OF SOME ANALOGUES OF NUCLEIC ACIDS COMPONENTS
- CHAPTER 7. THE SYNTHESIS OF BIOLOGICALLY RELEVANT MOLECULES VIA PHOSPHORUS YLIDS
- CHAPTER 8. THE PHOSPHATE TRANSFER PROCESS
- CHAPTER 9. PHOSPHATE SYNTHESIS, EXCHANGE AND INTERACTION IN NUCLEOTIDES AND RELATED COMPOUNDS
- CHAPTER 10. CHIRAL ANTICANCER OXAZAPHOSPHORINANES - STEREOSPECIFIC SYNTHESIS, CONFIGURATIONAL ASSIGNMENTS AND BIOLOGICAL EVALUATIONS
- CHAPTER 11.SYNTHETIC POLYNUCLEOTIDES AS INTERFERON INDUCERS
- CHAPTER 12. THE CASE FOR MONOMERIC METAPHOSPHATE
- CHAPTER 13. NUCLEOSIDE PHOSPHOROTHIOATES -TOOLS FOR THE INVESTIGATION OF ENZYME MECHANISMS
- CHAPTER 14. THE STEREOCHEMICAL COURSE OF SEVERAL ENZYME CATALYZED REACTIONS AT THE PHOSPHODIESTER LEVEL
- CHAPTER 15. MODELS OF BIOPOLYMERS BY RING OPENING POLYMERIZATION OF CYCLIC PHOSPHORUS CONTAINING COMPOUNDS
- CHAPTER 16. SOME ASPECTS OF OLIGONUCLEOTIDE SYNTHESIS
- CHAPTER 17. APPLICATIONS OF 31PNMR TOBIOLOGICAL SYSTEMS WITH EMPHASIS ON INTACT TISSUE DETERMINATIONS
- CHAPTER 18. OLIGODEOXYRIBONUCLEOTIDE HIGH SPEED SOLID PHASE SYNTHESIS AS A MOLECULAR BIOLOGY RESEARCH INSTRUMENT
- CHAPTER 19.CHEMICAL SYNTHESIS OF DNA POSSIBILITIES AND APPLICATIONS
- CHAPTER 20. SILYL- AND STANNYL-ESTERS OF PHOSPHORUS OXYACIDS — INTERMEDIATES FOR THE SYNTHESIS OF PHOSPHATE DERIVATIVES OF BIOLOGICAL INTEREST
- CHAPTER 21. THE USE OF DIETHYL AZODICARBOXYLATE-TRIPHENYLPHOSPHINE SYSTEM IN THE SYNTHESIS AND TRANSFORMATION OF NATURAL PRODUCTS
- CHAPTER 22. NUCLEOSIDE PHOSPHATES AS PROBES OF THE MECHANISM OF PROTEIN BIOSYNTHESIS