eBook - PDF
Small Molecular Immunomodifiers of Microbial Origin
Fundamental and Clinical Studies of Bestatin
- 269 pages
- English
- PDF
- Available on iOS & Android
eBook - PDF
Small Molecular Immunomodifiers of Microbial Origin
Fundamental and Clinical Studies of Bestatin
About this book
Small Molecular Immunomodifiers of Microbial Origin: Fundamental and Clinical Studies of Bestatin focuses on the results of experimental and clinical studies suggesting that bestatin and small molecular weight immunity-enhancing agents can contribute to the treatment of cancer and resistant infections. The selection first offers information on the screening, discoveries, and genetics of microbial secondary metabolites and activity of bestatin. Topics include the effect of bestatin on colony formation of murine bone marrow progenitor cells in vitro; antitumor effect of bestatin on murine transplantable tumors; and structures and properties of bestatin, amastatin, forphenicine, and esterastin. The text then examines the effects of bestatin on DNA and RNA metabolism in T-cells and levamisole and bestatin in immunodefficient aged mice. The text examines the influence of bestatin on the lymphoid system in humans, natural killer activity, and bone marrow. The preliminary phase I study of bestatin in lung cancer cases and malignant skin tumors are discussed. Topics include dosage schedule, clinical findings, and changes in immunological parameters. The selection is a vital reference for readers interested in the applications of bestatin in the treatment of cancer and resistant infections.
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Table of contents
- Front Cover
- Small Molecular Immunomodifiers of Microbial Origin: Fundamental and Clinical Studies of Bestatin
- Copyright Page
- Table of Contents
- PREFACE
- CHAPTER 1. SMALL MOLECULAR WEIGHT IMMUNOMODIFIERS PRODUCED BY MICROORGANISMS: THEIR SCREENING AND DISCOVERIES, AND THE GENETICS OF MICROBIAL SECONDARY METABOLITES
- CHAPTER 2. ACTIVITY OF BESTATIN: ENHANCEMENT OF IMMUNE RESPONSES AND ANTITUMOR EFFECT
- CHAPTER 3. EFFECT OF BESTATIN ON DNA AND RNA METABOLISM IN T-CELLS
- CHAPTER 4. LEVAMISOLE AND BESTATIN IN IMMUNODEFFICIENT AGED MICE
- CHAPTER 5. THE INFLUENCE OF BESTATIN ON THE LYMPHOID SYSTEM IN THE HUMAN
- CHAPTER 6. EFFECT OF BESTATIN ON NATURAL KILLER ACTIVITY
- CHAPTER 7. EFFECTS OF AN AMINOPEPTIDASE INHIBITOR (BESTATIN) ON HUMAN LYMPHOCYTES I. EFFECT ON POKEWEED MITOGEN-INDUCED IN VITRO IMMUNOGLOBULIN PRODUCTION
- CHAPTER 8. EFFECT OF BESTATIN ON BONE MARROW
- CHAPTER 9. PRELIMINARY PHASE I STUDY OF BESTATIN IN LUNG CANCER CASES
- CHAPTER 10. PHASE I STUDY OF BESTATIN: (I) A CLINICAL STUDY FOR DETERMINATION OF THE OPTIMAL DOSE OF BESTATIN
- CHAPTER 11. PHASE I STUDY OF BESTATIN: (II) CLINICAL TRIAL OF BESTATIN IN MALIGNANT SKIN TUMORS
- CHAPTER 12. PHASE I AND PRELIMINARY PHASE II CLINICAL TRIALS OF BESTATIN
- CHAPTER 13. CLINICAL EXPERIENCES IN THE USE OF BESTATIN IN THE TREATMENT OF LOCALLY ADVANCED CANCERS: CASE REPORT
- CHAPTER 14. CLINICAL EXPERIENCE WITH BESTATIN IN HEAD AND NECK CANCER
- CHAPTER 15. CLINICAL AND EXPERIMENTAL STUDY OF BESTATIN FOR ESOPHAGEAL CANCER
- CHAPTER 16. CLINICAL EFFECT OF BESTATIN ON MALIGNANT TUMORS OF FEMALE GENITAL ORGANS
- CHAPTER 17. PHARMACOKINETICS AND METABOLISM OF BESTATIN IN HUMANS AND RATS BY GAS CHROMATOGRAPHY-MASS SPECTROMETRY
- APPENDIX: METHODS OF TESTING HUMAN IMMUNE RESPONSES
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Yes, you can access Small Molecular Immunomodifiers of Microbial Origin by Hamao Umezawa in PDF and/or ePUB format, as well as other popular books in Physical Sciences & Chemistry. We have over 1.5 million books available in our catalogue for you to explore.