Mechanisms of Chemical Carcinogenesis
eBook - PDF

Mechanisms of Chemical Carcinogenesis

  1. 144 pages
  2. English
  3. PDF
  4. Available on iOS & Android
eBook - PDF

Mechanisms of Chemical Carcinogenesis

About this book

Mechanisms of Chemical Carcinogenesis provides information pertinent to the fundamental mechanisms of chemical carcinogenesis. This book surveys the interactions of chemical carcinogens with native DNA, the activation of normal cellular sequences, and the transforming role of the activated genes. Organized into seven chapters, this book begins with an overview of the relationship between the incidence of lung cancer and the frequency and duration of cigarette smoking. This text then examines the concept that carcinogens may require metabolic activation before they initiate carcinogenesis. Other chapters consider the structure of the nucleoside adducts resulting from the hydrolysis of salmon-sperm DNA and rat-liver ribosomal RNA. This book discusses as well the persistence of nucleoside analogues in target-tissue nucleic acid. The final chapter deals with mutational theory. This book is a valuable resource for workers involved with cancer research, toxicology, and molecular biology. Specialists in drug development, industrial hygiene and occupational medicine will also find this book useful.

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Yes, you can access Mechanisms of Chemical Carcinogenesis by D. E. Hathway in PDF and/or ePUB format, as well as other popular books in Medicine & Diseases & Allergies. We have over one million books available in our catalogue for you to explore.

Information

Publisher
Butterworth-Heinemann
Year
2013
Print ISBN
9780408115704
eBook ISBN
9781483192468
Topic
Medicine
Subtopic
Diseases & Allergies

Table of contents

  1. Front Cover
  2. Mechanisms of Chemical Carcinogenesis
  3. Copyright Page
  4. Table of Contents
  5. Dedication
  6. Preface
  7. Abbreviations
  8. Chapter 1. Introduction
  9. Chapter 2. Activation of chemical carcinogens in the mammal
  10. Chapter 3. Authenticated interactions with nucleic acid
  11. Chapter 4. Mechanisms in perspective: biological significance of modified deoxyribonucleoside residues in DNA
  12. Chapter 5. Mechanisms in perspectives: inhibition of tumour induction
  13. Chapter 6. Mechanisms in perspective: tumour promotion
  14. Chapter 7. Standard mutational theory of cancer and the impact of contingent advances in genetics
  15. Index