Drug Design
eBook - PDF

Drug Design

Medicinal Chemistry: A Series of Monographs, Vol. 2

  1. 666 pages
  2. English
  3. PDF
  4. Available on iOS & Android
eBook - PDF

Drug Design

Medicinal Chemistry: A Series of Monographs, Vol. 2

About this book

Drug Design, Volume II covers the design of bioactive compounds interacting with enzymes and playing a role in enzyme synthesis. The book discusses the modulation of pharmacokinetics by molecular manipulation; the factors in the design of reversible and irreversible enzyme inhibitors; and the design of organophosphate and carbamate inhibitors of cholinesterases. The text also describes the design of reactivators for irreversibly blocked acetylcholinesterase; drug design based on the inhibition of protein synthesis in the context of susceptible enzymic reactions; as well as the role of enzymes and their synthesis as a target for antibiotic action. The rational design of antiviral agents; the design of penicillin; the design of peptide hormone analogs; as well as the advances in the design of diuretics are also considered. The book further tackles the design of biologically active steroids; the rational elements in the development of superior neuromuscular blocking agents; and the design of tumor-inhibitory alkylating drugs. Pharmacologists, chemists, and people involved in drug design will find the book invaluable.

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Yes, you can access Drug Design by E. J. Ariëns in PDF and/or ePUB format, as well as other popular books in Medicine & Pharmacology. We have over one million books available in our catalogue for you to explore.

Information

Publisher
Academic Press
Year
2013
Print ISBN
9780120603022
eBook ISBN
9781483216041
Topic
Medicine
Subtopic
Pharmacology

Table of contents

  1. Front Cover
  2. Drug Design
  3. Copyright Page
  4. Table of Contents
  5. List of Contributors
  6. Preface
  7. Introduction
  8. Contents of Other Volumes
  9. Chapter 1. Modulation of Pharmacokinetics by Molecular Manipulation
  10. Chapter 2. Factors in the Design of Reversible and Irreversible Enzyme Inhibitors
  11. Chapter 3. The Design of Organophosphate and Carbamate Inhibitors of Cholinesterases
  12. Chapter 4. The Design of Reactivators for Irreversibly Blocked Acetylcholinesterase
  13. Chapter 5. Inhibition of Protein Biosynthesis: Its Significance in Drug Design
  14. Chapter 6. Enzymes and Their Synthesis as a Target for Antibiotic Action
  15. Chapter 7. The Rational Design of Antiviral Agents
  16. Chapter 8. Design of Penicillins
  17. Chapter 9. The Design of Peptide Hormone Analogs
  18. Chapter 10. Recent Advances in the Design of Diuretics
  19. Chapter 11. Design of Biologically Active Steroids
  20. Chapter 12. Rational Elements in the Development of Superior Neuromuscular Blocking Agents
  21. Chapter 13. The Design of Tumor-Inhibitory Alkylating Drugs
  22. Author Index
  23. Subject Index