Drug Design

Medicinal Chemistry: A Series of Monographs, Vol. 10

E. J. Ariëns

• Publisher: Academic Press
• Year: 2013
• Print ISBN:
  9780120603107
• eBook ISBN:
  9781483216119
• Topic: Medicine
• Subtopic: Pharmacology

Drug Design, Volume X covers promising and current developments in drug design. The book discusses procedures as applied in the practice of drug design; the structural aspects of the structure-activity relationships of neuroleptics; and promising perspectives in the highly actual field of bioactive peptides. The text also describes the application of the dynamic systems analysis to the antihypertensive drug action; polymeric drug delivery systems; and the design of biocompatible polymers. The structure-activity relationships of insect repellents as a basis for the design of such agents, as well as the approaches to the multivariate data analysis in structure-activity relationships, which is an essential aspect of drug design, are also encompassed. Chemists, pharmacologists, bioengineers, and people involved in drug design and manufacture will find the book invaluable.

Table of contents

• Front Cover
• Drug Design
• Copyright Page
• Table of Contents
• List of Contributors
• Preface
• Chapter 1. Practical Procedures in Drug Design
• Chapter 2. Structural Aspects of the Structure-Activity Relationships of Neuroleptics: Principles and Methods
• Chapter 3. Bridging the Gap between Bioactive Peptides and Nonpeptides: Some Perspectives in Design
• Chapter 4. Dynamic Systems Analysis as a Basis for Drug Design: Application to Antihypertensive Drug Action
• Chapter 5. Polymeric Drug Delivery Systems
• Chapter 6. The Design of Biocompatible Polymers
• Chapter 7. The Design of Insect Repellents
• Chapter 8. Multivariate Data Analysis in Structure–Activity Relationships
• Chapter 9. The Masca Model of Pharmacochemistry: II. Rational Empiricisms in the Multivariate Analysis of Opioids
• Index
• Contents of Other Volumes