Drug Design
eBook - PDF

Drug Design

Medicinal Chemistry: A Series of Monographs, Vol. 5

  1. 374 pages
  2. English
  3. PDF
  4. Available on iOS & Android
eBook - PDF

Drug Design

Medicinal Chemistry: A Series of Monographs, Vol. 5

About this book

Drug Design, Volume V covers the fundamental approaches to the development of bioactive compounds. The book discusses the utilization of operational schemes for analog synthesis in drug design; the design of enzyme inhibitors (transition state analogs); and the significance of structure-absorption-distribution relationships for drug design. The text describes the role of charge-transfer processes in the action of bioactive materials, as well as the approaches to the rational combination of antimetabolites for cancer chemotherapy. The physicochemical, quantum chemical, and other theoretical techniques for the understanding of the mechanism of action of central nervous system (CNS) agents, such as psychoactive drugs, narcotics, and narcotic antagonists and anesthetics, are also encompassed. Chemists, biochemists, pharmacologists, and people involved in drug design will find the book invaluable.

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Yes, you can access Drug Design by E. J. Ariëns in PDF and/or ePUB format, as well as other popular books in Medicine & Pharmacology. We have over one million books available in our catalogue for you to explore.

Information

Publisher
Academic Press
Year
2013
Print ISBN
9780120603053
eBook ISBN
9781483216072
Topic
Medicine
Subtopic
Pharmacology

Table of contents

  1. Front Cover
  2. Drug Design
  3. Copyright Page
  4. Table of Contents
  5. List of Contributors
  6. Preface
  7. Contents of Other Volumes
  8. Chapter 1. Utilization of Operational Schemes for Analog Synthesis in Drug Design
  9. Chapter 2. The Design of Enzyme Inhibitors: Transition State Analogs
  10. Chapter 3. Structure-Absorption-Distribution Relationships: Significance for Drug Design
  11. Chapter 4. The Role of Charge-Transfer Processes in the Action of Bioactive Materials
  12. Chapter 5. Approaches to the Rational Combination of Antimetabolites for Cancer Chemotherapy
  13. Chapter 6. Physicochemical, Quantum Chemical, and Other Theoretical Techniques for the Understanding of the Mechanism of Action of CNS Agents: Psychoactive Drugs,Narcotics, and Narcotic Antagonists and Anesthetics
  14. Index