Drug Design

Medicinal Chemistry: A Series of Monographs, Vol. 6

E. J. Ariëns

• Publisher: Academic Press
• Year: 2013
• Print ISBN: 9780120603060
• eBook ISBN: 9781483216089
• Topic: Medicine
• Subtopic: Pharmacology

Drug Design, Volume VI covers practical approaches to the development of bioactive compounds, with focus on antiradiation agents, organ-imaging radiopharmaceuticals, X-ray contrast media, proteinase inhibitors, and pesticide formulations. The book discusses the chemical routes available for the synthesis of diphenhydramine derivatives, the biological activities, the relationships between structure and activity, and the phase of manipulation in the design of diphenhydramine derivatives. The text also describes the design of antiradiation agents, organ-imaging radiopharmaceuticals, and X-ray contrast media, as well as the rational approach to proteinase inhibitors. The chemical and physical methods of formulation of agricultural pesticides are also encompassed. Chemists, biochemists, pharmacologists, and people involved in drug design and manufacture will find the book invaluable.

Table of contents

• Front Cover
• Drug Design
• Copyright Page
• Table of Contents
• List of Contributors
• Preface
• Contents of Other Volumes
• Chapter 1. Diphenhydramine Derivatives: Through Manipulation toward Design
• Chapter 2. The Design of Antiradiation Agents
• Chapter 3. Rational Approach to Proteinase Inhibitors
• Chapter 4. The Design of Organ-Imaging Radiopharmaceuticals
• Chapter 5. Design of X-Ray Contrast Media
• Chapter 6. Agricultural Pesticides: Chemical and Physical Methods of Formulation
• Subject Index