Biological Response Mediators and Modulators
eBook - PDF

Biological Response Mediators and Modulators

John Jacob Abel Symposia on Drug Development

  1. 274 pages
  2. English
  3. PDF
  4. Available on iOS & Android
eBook - PDF

Biological Response Mediators and Modulators

John Jacob Abel Symposia on Drug Development

About this book

Biological Response Mediators and Modulators explains that the behavior of a cell depends upon the absorption of the ligand, the quantity of functional receptors existing for ligand recognition and binding, and the transduction of the signal through successive intercellular events. The book presents such model systems as the low-density lipoprotein (LDL) receptor, the epidermal growth factor receptor, and the insulin receptor. The LDL receptor is a model for a class of surface receptors that facilitate the cellular application of macromolecules through the process of receptor-mediated endocytosis. The book discusses the general characteristics of receptor-mediated endocytosis. Another topic of interest is the property of growth-related cell surface receptors. The section that follows describes the function of these receptors as tyrosine-specific protein kinases, which is related to the protein yields of some viral oncogenes. The amount of receptors in a cell depends upon the rates of synthesis and inactivation. The book will provide valuable insights for scientists, cytologists, students, and researchers in the field of chemistry.

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Yes, you can access Biological Response Mediators and Modulators by J. Thomas August in PDF and/or ePUB format, as well as other popular books in Medicine & Pharmacology. We have over one million books available in our catalogue for you to explore.

Information

Publisher
Academic Press
Year
2013
Print ISBN
9780120680504
eBook ISBN
9781483216256
Topic
Medicine
Subtopic
Pharmacology

Table of contents

  1. Front Cover
  2. Biological Response Mediators and Modulators
  3. Copyright Page
  4. Table of Contents
  5. Contributors
  6. Preface
  7. Acknowledgments
  8. CHAPTER 1. RECEPTOR-MEDIATED ENDOCYTOSIS AS EXEMPLIFIED BY THE LOW DENSITY LIPOPROTEIN RECEPTOR
  9. CHAPTER 2. THE RECEPTOR FOR EGF FUNCTIONS AS A TYROSINE-SPECIFIC PROTEIN KINASE
  10. CHAPTER 3. REGULATION OF INSULIN RECEPTOR METABOLISM: MECHANISM OF INSULIN-INDUCED RECEPTOR DOWN-REGULATION
  11. CHAPTER 4. METABOLISM OF ARACHIDONIC ACID BY THE CYCLOOXYGENASE PATHWAY IN MAST CELLS AND BY THE 15- LIPOXYGENASE PATHWAY IN HUMAN EOSINOPHILS
  12. CHAPTER 5. PHYSIOLOGIC AND PATHOBIOLOGIC EFFECTS OF LEUKOTRIENES C4, D4, AND E4
  13. CHAPTER 6. BIOLOGICAL ACTVITIES OF LEUKOTRIENE B4 AND OTHER HYDROXYEICOSATETRAENOIC ACIDS (HETEs)
  14. CHAPTER 7. ACETYL GLYCERYL ETHER PHOSPHORYLCHOLINE (AGEPC) A MODEL ANAPHYLACTOMIMETIC MEDIATOR
  15. CHAPTER 8. THE ROLE OF LIPOXYGENASE PRODUCTS OF ARACHIDONIC ACID IN INFLAMMATORY EVENTS MEDIATED BY HUMAN BASOPHILS AND MAST CELLS
  16. CHAPTER 9. THE CHEMISTRY AND BIOLOGY OF C3a, C4a, AND C5a AND THEIR EFFECTS ON CELLS
  17. CHAPTER 10. ON THE SIZE HETEROGENEITY AND MOLECULAR COMPOSITION OF THE TRANS-MEMBRANE CHANNELS PRODUCED BY COMPLEMENT
  18. CHAPTER 11. MEMBRANE DAMAGE BY COMPLEMENT COMPONENTS C5b-C9: BIOCHEMICAL AND ULTRASTRUCTURAL STUDIES
  19. CHSPTER 12. CYTOKINE-CELL INTERACTIONS THAT MODULATE INFLAMMATORY REACTIONS
  20. CHAPTER 13. INTERLEUKIN-2 AND THE REGULATION OF CYTOTOXIC CELLS
  21. CHAPTER 14. PHARMACOLOGICAL MODULATIONS OF IgE-BINDING FACTOR
  22. CHAPTER 15. MECHANISMS OF ANTIVIRAL ACTION OF INTERFERONS
  23. CHAPTER 16. PHARMACOLOGICAL MANIPULATION OF THE CHEMOTACTIC FACTOR RECEPTOR ON LEUKOCYTES
  24. CHAPTER 17. SECRETORY PRODUCTS IN CYTOTOXICITY
  25. T Cells
  26. CHAPTER 18. ANTIBODY-MEDIATED TUMOR SUPPRESSION: POSSIBLE ROLE OF LYSOPHOSPHATIDYLCHOLINE AND INTERLEUKIN
  27. Index