
- 656 pages
- English
- PDF
- Available on iOS & Android
The Molecular Biology of Cancer
About this book
The Molecular Biology of Cancer discusses the state of progress in the molecular biology of cancer. The book describes the effects of anticancer agents on nucleolar ultrastructure; the role of chromosomes in the causation and progression of cancer and leukemia; the replication, modification, and repair of DNA. The text also describes the metabolism and utilization of messenger RNA and other high molecular weight RNA and low molecular weight nuclear RNA; the characteristics, structures, and functions of nuclear proteins; and the process of protein synthesis. Nucleotides are reviewed with regard to its biosynthesis, inhibition of synthesis, and development of resistance to inhibitors. The book further tackles the biochemical mechanisms of chemical carcinogenesis; the oncogenic viruses; and the molecular correlation concept. The text also demonstrates phenotypic variability as a manifestation of translational control; and plasmacytomas. Molecular biologists, virologists, pathologists, cell biologists, oncologists, pharmacologists, and students taking related courses will find the book useful.
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Information
Table of contents
- Front Cover
- The Molecular Biology of Cancer
- Copyright Page
- Table of Contents
- Dedication
- List of Contributors
- Preface
- Acknowledgments
- Chapter I. Introduction
- Chapter II. The Nucleus of the Cancer Cell
- Chapter III. Chromosomes in the Causation and Progression of Cancer and Leukemia
- Chapter IV. DNA: Replication, Modification, and Repair
- Chapter V. Messenger RNA and Other High Molecular Weight RNA
- Chapter VI. Low Molecular Weight Nuclear RNA
- Chapter VII. Nucleotides: Biosynthesis, Inhibition of Synthesis, and Development of Resistance to Inhibitors
- Chapter VIII. Nuclear Proteins
- Chapter IX. Protein Synthesis
- Chapter X. Biochemical Mechanisms of Chemical Carcinogenesis
- Chapter XI. Oncogenic Viruses
- Chapter XII. Molecular Correlation Concept
- Chapter XVIII. Phenotypic Variability as a Manifestation of Translational Control
- Chapter XIV. Plasmacytomas
- Epilogue
- Author Index
- Subject Index