
- 255 pages
- English
- ePUB (mobile friendly)
- Available on iOS & Android
eBook - ePub
About this book
Intense immunosuppression followed by Hematopoietic Stem Cell Transplantation for Neurological Diseases (HSCT) has been evaluated as a possible therapeutic tool in severe autoimmune diseases for the last 20 years. In the neurological field, HSCT has been widely investigated for the treatment of multiple sclerosis and evidence is accumulating about its potential use in neuromyelitis optica, stiff person syndrome, myasthenia gravis and many immune neuropathies. This volume summarizes that research. Besides their strong clinical relevance, studies on HSCT in neurological diseases have contributed to mew insights on the pathological mechanisms underlying CNS autoimmunity.
- Reviews immunological mechanisms of HSCT and CNS autoimmunity
- Identifies neurological diseases showing treatment efficacy with HSCT
- Includes MS, myasthenia gravis, neuromyelitis optica, and more
- Covers early and late side effects of HSCT
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Yes, you can access Hematopoietic Stem Cell Transplantation for Neurologic Diseases by in PDF and/or ePUB format, as well as other popular books in Medicine & Neurology. We have over one million books available in our catalogue for you to explore.
Table of contents
- Cover image
- Title page
- Table of Contents
- Series Page
- Copyright
- Handbook of Clinical Neurology 3rd Series
- Dedication
- Foreword
- Preface
- Contributors
- Chapter 1: Introduction to HSCT for neurologic diseases
- Chapter 2: Modification of T- and B-cell-associated immuno-pathologic mechanisms in multiple sclerosis by disease modifying therapies: Achievements and opportunities
- Chapter 3: The hematopoietic niche and the autoreactive memory in autoimmune disorders
- Chapter 4: The preclinical data and immunologic rationale for hematopoietic stem cell transplantation in autoimmunity
- Chapter 5: Immune cell reconstitution following autologous hematopoietic stem cell transplantation in multiple sclerosis
- Chapter 6: Immune reconstitution in rheumatic disease patients after autologous hematopoietic stem cell transplantation
- Chapter 7: The role of chemotherapy in hematopoietic stem cell transplantation for autoimmune disorders: From lymphoablative to myeloablative conditioning protocols
- Chapter 8: The HSCT procedure (I): Mobilization, collection, manipulation, and cryopreservation of a HSC graft
- Chapter 9: The HSCT procedure (II): Conditioning, hematopoietic stem cell infusion, supportive care, and monitoring
- Chapter 10: Early and late complications of hematopoietic stem cell transplantation
- Chapter 11: Hematopoietic stem cell transplantation for multiple sclerosis
- Chapter 12: Hematopoietic stem cell transplantation for neuromyelitis optica spectrum disorder. Can immune tolerance be reestablished?
- Chapter 13: Hematopoietic stem cell transplantation (HSCT) for chronic inflammatory demyelinating polyradiculoneuropathy (CIDP): Is it CIDP?
- Chapter 14: HSCT for stiff person syndrome and myasthenia gravis
- Chapter 15: Autologous hematopoietic stem cell transplantation for pediatric autoimmune neurologic disorders
- Chapter 16: HSCT for systemic autoimmune diseases with neurologic involvement
- Chapter 17: Hematopoietic stem cell therapy and ex vivo gene therapy for X-linked adrenoleukodystrophy
- Chapter 18: Economics of hematopoietic stem cell transplant in immune-mediated neurologic autoimmune diseases
- Chapter 19: The EBMT-ADWP and the CIBMTR
- Chapter 20: Ongoing randomized clinical trials on HSCT in multiple sclerosis
- Index