TRP Channels as Therapeutic Targets
eBook - ePub

TRP Channels as Therapeutic Targets

Advances in Basic Science and Clinical Use

  1. 550 pages
  2. English
  3. ePUB (mobile friendly)
  4. Available on iOS & Android
eBook - ePub

TRP Channels as Therapeutic Targets

Advances in Basic Science and Clinical Use

About this book

TRP Channels as Therapeutic Targets, Second Edition is a comprehensive reference on the roles of TRP Channels in health and disease states. The Editor lined up a team of worldwide experts in academia and corporate R&D to provide diverse views into these promising drug development targets. Following the research development happened in the past ten years, since the first edition published, the revision includes seven new chapters. All remaining chapters are completely updated. New topics included in the book are TRP channels biology, the crystalline structure of TRP channels, targeting TRP channels for pain relief, the relationship with migraine, emerging pain targets, a comprehensive view of the role of TRP channels in respiratory diseases and COVID complications, anxiety relief, renal disease, arthritis, and therapeutic opportunities for thermal regulation. TRP Channels as Therapeutic Targets, Second Edition is a reference for broad segments of the scientific and medical community. Researchers working on TRP channel drug discovery will benefit from the overview of applications to conditions in specific organ systems. Clinicians interested in new drugs in the pipeline, will find in this book their biologic principles of action. - Presents the perspectives of several life science research specialties on the topic - Provides a comprehensive picture of the TRP field, from TRP channel dysfunction through TRP drug discovery and development to clinical trials and everyday medical practice - Represents an updated and complete reference

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Yes, you can access TRP Channels as Therapeutic Targets by Arpad Szallasi in PDF and/or ePUB format, as well as other popular books in Medicine & Biochemistry in Medicine. We have over one million books available in our catalogue for you to explore.

Information

Publisher
Academic Press
Year
2024
eBook ISBN
9780443186547
Edition
2
Topic
Medicine
Subtopic
Biochemistry in Medicine

Table of contents

  1. Title of Book
  2. Cover image
  3. Title page
  4. Table of Contents
  5. Copyright
  6. Contributors
  7. Preface
  8. Chapter 1 Opening remarks: What makes TRP channels attractive therapeutic targets?
  9. Chapter 2 Biology of TRP channels
  10. Chapter 3 Targeting TRP channels: The emerging role of cryogenic electron microscopy in drug discovery
  11. Chapter 4 Thermo-TRPs: Temperature-sensitive TRP channels
  12. Chapter 5 “TRP channelopathies”: TRP channel dysfunction in hereditary diseases
  13. Chapter 6 Current understanding of TRP channels and their genomics: Implications in health research
  14. Chapter 7 TRP channel drug discovery strategies
  15. Chapter 8 High-dose capsaicin patch for pain relief: Clinical experience
  16. Chapter 9 Therapeutic uses of injectable capsaicin for pain
  17. Chapter 10 Resiniferatoxin for permanent pain relief in cancer patients
  18. Chapter 11 TRPV1 antagonists: Future drug discovery directions
  19. Chapter 12 TRPA1 antagonists for pain relief
  20. Chapter 13 TRPM3: An emerging pain target (and more)
  21. Chapter 14 TRP channels and migraine
  22. Chapter 15 TRP channels in the GU tract
  23. Chapter 16 TRP channels in respiratory disorders
  24. Chapter 17 TRP channels: Emerging targets in COVID-19 and its complications
  25. Chapter 18 TRP channels in cardiovascular disease
  26. Chapter 19 TRP channels in cerebral vascular disorders
  27. Chapter 20 TRPV1 in blood pressure regulation: A new therapeutic target in hypertension?
  28. Chapter 21 Activating, inhibiting, and hijacking TRP channels for relief from itch
  29. Chapter 22 TRP channels in dermatology
  30. Chapter 23 Transient Receptor Potential (TRP) channels in cancer: Implications for drug discovery and development
  31. Chapter 24 TRP channel expression in the tumor microenvironment: Implications for tumor progression and metastasis
  32. Chapter 25 TRP channels as potential target molecules for pharmacotherapy of neurological diseases
  33. Chapter 26 Targeting TRP channels for anxiety relief and improving mental health
  34. Chapter 27 Potential of agents that modulate transient receptor potential (TRP) channels as therapies in arthritis
  35. Chapter 28 TRP channels as molecular targets to relieve endocrine-related diseases
  36. Chapter 29 Transient receptor potential (TRP) channels in metabolic syndrome
  37. Chapter 30 TRP channels in renal disease. Lessons from Polycystin-2 (TRPP2)
  38. Chapter 31 TRP channels and thermoregulation; therapeutic opportunities
  39. Chapter 32 Concluding remarks: Past, present, future
  40. Index