
- 296 pages
- English
- ePUB (mobile friendly)
- Available on iOS & Android
Superoxide Ion Chemistry and Biological Implications
About this book
The chemical properties of superoxide ion, its biological role, and the role of other oxygen radicals which arise as a result of its transformations are contained in this text. In Volume I the principal reactions of superoxide ion, including protonation reactions with proton donors, nucleophilic reactions with esters, alkyl halides and other compounds, electron transfer reactions with quinones and metal complexes, are described. Basic quantitative data including rate constants and yields for the reactions of superoxide ion of all types are given in tables. This volume contains the mechanisms of the generation of oxygen radicals in cells and the interaction of superoxide ion with cell components. The role of superoxide ion in lipid peroxidation and destruction of proteins and nucleic acids is explained, as well as oxygen radicals in the mechanisms of toxic and therapeutic action of drugs, especially anticancer antibiotics. In addition, the action of superoxide ion and other oxygen radicals on plants, micro-, and macroorganisms is discussed, along with the role of oxygen radicals in normal metabolic and pathological processes.
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Information
Table of contents
- Cover
- Title Page
- Copyright Page
- Preface
- The Author
- Table of Contents
- Chapter 1 Physical Properties of Superoxideion
- Chapter 2 Detection of Superoxide Ion
- Chapter 3 Methods of the Generation and Modes of the Formation of Superoxide Ion
- Chapter 4 Reactivity of Superoxide Ion
- Chapter 5 Deprotonation and Deprotonation-Oxidation Reactions by Superoxide Ion
- Chapter 6 Nucleophilic Reactions of Superoxide Ion
- Chapter 7 One-Electron Transfer Reactions of Superoxide Ion
- Chapter 8 The Formation of Superoxide Adducts by Metal Complexes
- Chapter 9 Generation of Active Oxygen Species by Superoxide Ion: The Formation of HO,HO2· , HO2.−, and H2O2
- Chapter 10 The Interaction of Superoxide Ion with Natural Compounds
- Conclusions
- Appendix
- Index