Recombinant Poxviruses
eBook - ePub

Recombinant Poxviruses

  1. 368 pages
  2. English
  3. ePUB (mobile friendly)
  4. Available on iOS & Android
eBook - ePub

Recombinant Poxviruses

About this book

Recombinant Poxviruses provides a comprehensive examination of poxviruses with an emphasis on the potential of these viruses as new vaccines. The book considers a wide range of issues involved in producing new genetically engineered live vaccines, such as efficacy, safety, stability, cost, host range, immune response, immunization route, use of multivalent vaccines, and need for revaccination. The opening chapter describes the origin of vaccinia virus, its use to eradicate smallpox, and the pathogenesis of poxvirus infections. Subsequent chapters examine the molecular biology of poxviruses, methods of constructing vaccinia virus recombinants, and applications; the use and immune responses induced by poxvirus recombinants as live vaccines; and the important issues of the safety and immunogenicity of vaccinia virus. The book's final two chapters report the progress that has been made developing avipoxviruses and parapoxviruses as candidate recombinant vaccines. Recombinant Poxviruses will be a welcome addition to the bookshelves of virologists, microbiologists, infectious disease specialists, and veterinarians.

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Yes, you can access Recombinant Poxviruses by Matthew M. Binns,Geoffrey L. Smith in PDF and/or ePUB format, as well as other popular books in Medicine & Infectious Diseases. We have over one million books available in our catalogue for you to explore.

Information

Publisher
CRC Press
Year
2024
eBook ISBN
9781040288306
Edition
0
Topic
Medicine
Subtopic
Infectious Diseases

Table of contents

  1. Cover
  2. Title
  3. Copyright
  4. Preface
  5. The Editors
  6. Contributors
  7. Table of Contents
  8. Chapter 1 Vaccinia Virus as a Vaccine, and Poxvirus Pathogenesis
  9. Chapter 2 Molecular Biology of Poxviruses
  10. Chapter 3 The Design, Construction, and Use of Vaccinia Virus Recombinants
  11. Chapter 4 Poxvirus Recombinants as Live Vaccines
  12. Chapter 5 Development and Deliberate Release of a Vaccinia-Rabies Recombinant Virus for the Oral Vaccination of Foxes Against Rabies
  13. Chapter 6 Immunogenicity and Antigen Presentation
  14. Chapter 7 Safety and Attenuation of Vaccinia Virus
  15. Chapter 8 Avipoxvirus Vectors
  16. Chapter 9 Parapoxviruses: Their Biology and Potential as Recombinant Vaccines
  17. Index