Immunology of Beh 's Disease
eBook - ePub

Immunology of Beh 's Disease

  1. 186 pages
  2. English
  3. ePUB (mobile friendly)
  4. Available on iOS & Android
eBook - ePub

Immunology of Beh 's Disease

About this book

Beh's Disease (BD) is one of the most-studied systemic disorders characterized by an occlusive vasculopathy of multiple organs. The etiology and pathogenesis of BD are still unclear, but there is evidence for genetic, immunologic and infectious factors in the onset and throughout the course of the disease. This book summarizes our knowledge regarding the most important factors that induce or trigger BD. After an epidemiological overview, the clinical presentation of ocular and non-ocular symptoms of BD is summarized. The immunopathological changes reflect a chronic vasculitis of arterioles, venules, and capillaries. The book covers the role of T-cells, NK-T-cells, secreted cytokines, and neutrophils as well as immune reactions against various microbial heat shock proteins. It shows that the pathogenic gene involved in the development of BD is pinpointed to HLA-B51. It also discusses the treatment of BD, including anti-TNF-alpha-antibodies and interferon-alpha.

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Yes, you can access Immunology of Beh 's Disease by Shigeaki Ohno,Manfred Zierhut in PDF and/or ePUB format, as well as other popular books in Medicine & Clinical Medicine. We have over one million books available in our catalogue for you to explore.

Information

Publisher
CRC Press
Year
2003
eBook ISBN
9781135301996
Edition
0
Topic
Medicine
Subtopic
Clinical Medicine

Table of contents

  1. Cover Page
  2. Half Title
  3. Title Page
  4. Copyright Page
  5. Table of Contents
  6. Foreword
  7. 1. Epidemiology of Adamantiades-Behçet’s Disease
  8. 2. A Proposal to Study the Frequency of Rare Diseases
  9. 3. Non-Ocular Manifestations
  10. 4. Ocular Manifestations in Behçet’s Disease
  11. 5. Immunohistopathology of Behçet’s Disease
  12. 6. T Cells in Behçet’s Disease
  13. 7. NK and NK-T Cells Possibly Involved in Behçet’s Disease
  14. 8. Cytokines in Behçet’s Disease
  15. 9. Autoimmunity in Behçet’s Disease
  16. 10. An Attempt To Create A Behçet’s Disease Model In Mice
  17. 11. Neutrophil Hyperfunction in Behçet’s Disease
  18. 12. Role of Infectious Organisms in Behçet’s Disease
  19. 13. The Role of Heat Shock Proteins in Behçet’s Disease
  20. 14. Association of HLA-B51 Suballeles with Behçet’s Disease in Patients of German and Turkish Origin
  21. 15. Peptide Motif of HLA-B*5101 and the Linkage To Behçet’s Disease
  22. 16. Microsatellite Mapping of the Pathogenic Gene of Behçet’s Disease
  23. 17. The Treatment of Behçet
  24. 18. The Efficacy of Anti-TNF-Alpha Antibody in the Treatment of Uveitis Patients with Behçet’s Disease
  25. 19. Use of Interferon-a in Behçet’s Disease
  26. 20. Type I Interferon Treatment of Experimental Autoimmune Uveoretinitis
  27. Authors
  28. Index