Genome Editing for Neurodegenerative Diseases: From Concept to Clinical Trials examines recent advances in neurodegenerative disease research and clinical challenges in practical applications. With an emphasis on genome editing tools such as ZFNs, TALENSs and CRISPR-Cas, this book sheds light on the possibilities to counteract genetic and neurodegenerative diseases. It will be of interest to researchers in neuroscience and biopharmaceuticals, as well as clinicians specializing in neurodegenerative diseases. - Covers basic mechanisms of genome-editing tools and their therapeutic potential - Highlights current research progress and therapeutic strategies to use genome-editing tools against neurodegenerative diseases - Includes research on genome-editing tool development, from basic concept to clinical trials

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Yes, you can access Genome Editing for Neurodegenerative Diseases by Sandeep Kumar Singh,Amarish Kumar Yadav,Burkhard Poeggeler,George Perry in PDF and/or ePUB format, as well as other popular books in Biological Sciences & Neuroscience. We have over one million books available in our catalogue for you to explore.

Information

Publisher

Academic Press

Year

2024

eBook ISBN

9780443238277

Edition

Topic

Biological Sciences

Subtopic

Neuroscience

Index

Biological Sciences

Title of Book
Cover image
Title page
Table of Contents
Copyright
List of contributors
Introduction
Chapter one Therapeutic potential of genome editing tools in neurodegenerative diseases
Chapter two Genetic and molecular basis of neurodegenerative diseases
Chapter three Genome editing tools: principles, structures, and mechanisms
Chapter four Advances in CRISPER/Cas system and genome editing technologies for the treatment of neurodegenerative diseases
Chapter five Use of CRISPR system in genetic screening to detect neurodegenerative disease
Chapter six Epigenetic manipulation and gene regulation using the CRISPR/Cas system for neurodegenerative diseases
Chapter seven Transgene delivery system: viral, nonviral, and other methods for central nervous system
Chapter eight Gene therapies for neurodegenerative disease: current knowledge and challenges
Chapter nine Gene therapy under clinical trials for neurodegenerative diseases
Chapter ten Clinical challenges and future prospective in use of gene-editing tools as neurotherapeutics
Index

About this book

Frequently asked questions

Information

Table of contents